Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Uncovering the Genetic Basis of Sex Determination in Amborella trichopoda

Although it is a complicated process, plant reproduction is essential to both ecological balance and the food chain. Some plants are hermaphrodites, some are either male or female, and some change sex during their lives.

26 Nov 2024

Novel Genetic Variant Associated with Severe Mitochondrial Dysfunction

The rare hereditary condition known as mitochondrial DNA depletion syndrome (MTDPS) is typified by a significant reduction in mitochondrial DNA (mtDNA).

26 Nov 2024

New Method for Understanding Brain Function and Dysfunction

An international group of researchers from FutureNeuro, the Research Ireland Centre for Translational Brain Science, and RCSI University of Medicine and Health Sciences have created a novel technique to characterize gene activity in the living human brain.

26 Nov 2024

Novel Approach to Lipid Nanoparticle Engineering

To enhance mRNA distribution, Penn engineers have created an ideal “recipe” for ionizable lipids, which are essential components of lipid nanoparticles (LNPs), the molecules that underlie the COVID-19 vaccines and other cutting-edge treatments.

25 Nov 2024

Overlapping Enhancers Challenge Traditional Genetic Models

The DNA of plants and animals contains their blueprint. However, genes, which are the instructions for generating proteins, are found in a very small portion of the genome roughly 2% in mammals.

25 Nov 2024

Cell Shape and Surface Stiffness Drive Distinct Migratory Behaviors in Ovarian Cancer Cells

The spread of tumor from the primary cancer site to distant organs, called metastasis, has puzzled scientists for many years – they are only now beginning to pinpoint triggers and mechanisms that drive this process.

25 Nov 2024

Self-Eliminating e-Drive System Reverses Insecticide Resistance in Fruit Flies

Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ineffective.

25 Nov 2024

New Vector Systems Open the Door for Efficient Genetic Modification

A recent breakthrough in biotechnology promises to change the landscape of plant genetic engineering. Imagine a persistent invader-;Agrobacterium-;long used to deliver genes into plants. Despite its historical success, the journey has been fraught with setbacks, especially with crops that launch fierce immune defenses.

25 Nov 2024

Unveiling the Hidden Potential of SnoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

25 Nov 2024

Simplified Model Predicts Neuronal Activity in Zebrafish Gaze Control

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze.

25 Nov 2024

Researchers Decode Complete Genome of Medicinal Plant Forsythia Suspensa

A recent study has decoded the complete genome of Forsythia suspensa, a plant renowned for its medicinal value and decorative appeal.

23 Nov 2024

Study Reveals Genetics Behind Dilated Cardiomyopathy

A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single "aberrant" genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College London and the MRC Laboratory of Medical Sciences.

23 Nov 2024

Rutgers Researchers Uncover How Brain Cells Form Functional Networks

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

23 Nov 2024

Scientists Identify Gene Variant Linked to Early Miscarriages in Women

In what could be a major advance in understanding the genetic causes underlying human infertility, scientists led by researchers from Rutgers University-New Brunswick have identified a gene variant directly tied to early miscarriages in women.

23 Nov 2024

EPFL Brain Models Break New Ground in Understanding Neural Connectivity

The hippocampus is one of the most fascinating brain regions. Associated with the formation of memories, it also helps us to navigate through the world without getting lost.

23 Nov 2024

Human Cell Atlas Consortium Makes Major Progress in Understanding the Human Body

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication today (20 November) of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

22 Nov 2024

Mapping of Mouse Intestine Sheds Light on Immune Control and Adaptability

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease.

22 Nov 2024

Chromosome Abnormalities Found in Healthy Women’s Breast Cells

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

22 Nov 2024

Researchers Map DNA Repair Protein Activity in Human Cells

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells.

22 Nov 2024