Lab Automation and Bioinformatics News and Research

Latest Lab Automation and Bioinformatics News and Research

Exercise Intervention Reduces Fat Accumulation Associated with Aging

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.

16 Apr 2024

New Delivery System Opens the Door to Gene-Silencing Therapy

The next generation of medications, known as antisense oligonucleotides (ASOs), works by preventing the transmission of damaging genetic messages.

16 Apr 2024

Cell's Garbage Disposal May Also Send Sensory Signals Beyond Recycling

The proteasome, the cell's garbage disposal mechanism, usually breaks down proteins into smaller pieces and recycles some of the pieces.

15 Apr 2024

Spinal Cord's Hidden Role in Learning Movement

A common misconception is that the spinal cord serves as a basic relay station that transmits signals from the brain to the body.

15 Apr 2024

Research Uncovers Genetic Basis of Macroalgae Multicellularity

A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or "seaweed," to evolve multicellularity.

15 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Plants can be temperamental. Even weeds along the side of highways or pushing their way up in the cracks of concrete sidewalks can get stressed out by dehydration, cold, excess salt and more.

13 Apr 2024

Unraveling the Molecular Mechanisms of DNA Entanglement Resolution

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

9 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

New Method Revolutionizes Assessment of Ferroptosis-Targeting Enzymes

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death.

8 Apr 2024

Nature's 'Molecular Kitchen': Heat Flows and the Origin of Life's Ingredients

Life is complicated. What is true for our everyday existence also holds for the many complex processes that take place inside cells

5 Apr 2024

Designing Compounds for Next-Gen Antibiotics and Cancer Treatments

Chemists at Cold Spring Harbor Laboratory (CSHL) have generated a novel set of molecular compounds and are evaluating them as possible candidates for novel drug discovery leads.

5 Apr 2024

Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive forms of disease.

5 Apr 2024

Breakthrough Study Reveals Genetic Variants with Significant Impact on Obesity Risk

A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.

5 Apr 2024

New Platform Reveals Individual Sensitivity to Disease-Causing Mutations

In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes-;the effect on the finished dish can be quite different, depending on the mix of other ingredients.

4 Apr 2024