Lab Automation and Bioinformatics News and Research

Latest Lab Automation and Bioinformatics News and Research

Novel Targets for Modulating the Gut Microbiota and Human Health

Researchers at the Helmholtz Institute for RNA-based Infection Research and the Julius-Maximilians-Universität in Würzburg have discovered a protein and a class of small ribonucleic acids (sRNAs) in Bacteroides thetaiotaomicron that control the metabolism of sugar.

10 Jan 2025

New Discovery Sheds Light on How Monoamines Regulate Brain Rhythms

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

9 Jan 2025

Echidna Genome Sheds Light on Complex Sex Chromosome Evolution

A nearly gapless genome sequence of the echidna, an egg-laying mammal with multiple sex chromosomes, helps researchers to track genomic reorganization events that gave rise to a highly unusual sex determination system.

9 Jan 2025

Identifying PRIMER Cells and their Role in Defense Signaling

A diverse population of immune cells that move from one organ to another and react to anything from cuts to colds to cancer is how human bodies protect themselves. However, this luxury is not available to plants.

9 Jan 2025

CryoSCAPE Enables Accurate Single-Cell Profiling in Diverse Populations

Human blood is a complex and delicate mixture, often used by researchers and clinicians to understand the body’s inner workings.

7 Jan 2025

Unexpected Role for CDKN2A Gene in Esophageal Cancer Progression

Scientists from the Barts Cancer Institute and the Francis Crick Institute have demonstrated that a genetic flaw that has long been thought to cause esophageal cancer may actually protect against the disease in its early stages.

6 Jan 2025

Genetic Discovery Offers Potential for Higher Crop Yields and Biofuel Production

A team of scientists with two Department of Energy Bioenergy Research Centers -; the Center for Bioenergy Innovation, or CBI, at Oak Ridge National Laboratory and the Center for Advanced Bioenergy and Bioproducts Innovation, or CABBI, at the University of Illinois Urbana-Champaign -; identified a gene in a poplar tree that enhances photosynthesis and can boost tree height by about 30% in the field and by as much as 200% in the greenhouse.

6 Jan 2025

Molecular Lantern Technique Could Revolutionize Brain Pathology Monitoring

Monitoring the changes caused in the brain at the molecular level by cancer and other neurological pathologies in a non-invasive way is one of the great challenges of biomedical research.

2 Jan 2025

New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

In a comprehensive Genomic Press Interview, renowned neuroscientist Dr. Michael Meaney reveals pivotal discoveries about the intricate relationship between genes and environment in shaping brain health.

2 Jan 2025

Ancient DNA Analysis Unveils Migration Patterns in Early Europe

Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analyzing ancestry with ancient DNA, in research led by the Francis Crick Institute.

2 Jan 2025

New Studies Investigate Microbial Interactions and Nutrient Exchange in Soils

Communities of microbes (microbiomes), particularly in soils, can be startlingly diverse, with as many as 10,000 species in just a cup of material.

27 Dec 2024

AI-Designed Nanocages Mimic Intricate Structures of Viruses

Professor Sangmin Lee from POSTECH's Department of Chemical Engineering, in collaboration with 2024 Nobel Chemistry Laureate Professor David Baker from the University of Washington, has developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence (AI).

26 Dec 2024

Fruit Flies Evolve New Defense Through Gene Transfer

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

26 Dec 2024

New Treatment Targets Tumor Microenvironment to Fight Breast Cancer

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War. It turns out that cancerous growths adopt this strategy in their battle against the immune system.

24 Dec 2024

Digital Twin Technology Reverses Colon Cancer in Study by KAIST Researchers

Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from the destruction of healthy cells.

24 Dec 2024

SMART Software Unlocks New Insights into Cellular Dynamics

Researchers at University of California San Diego have developed and tested a new software package, called Spatial Modeling Algorithms for Reactions and Transport (SMART), that can realistically simulate cell-signaling networks -; the complex systems of molecular interactions that allow cells to respond to diverse cues from their environment.

20 Dec 2024

Subsurface Microbial Life Reveals Surprising Diversity in Extreme Environments

Which microbes thrive below us in darkness – in gold mines, in aquifers, in deep boreholes in the seafloor – and how do they compare to the microbiomes that envelop the Earth's surfaces, on land and sea?

19 Dec 2024

Unveiling Human Stem Cell Model with Functional Notochord

For the first time, the notochord a tissue in the developing embryo that serves as a navigation system, telling cells where to build the spine and nervous system (the trunk) has been included in human stem cell models created by researchers at the Francis Crick Institute.

19 Dec 2024

Scientists Mimic Fungal Process to Create Novel Medicines

Since the unintentional 1928 discovery of penicillin by Alexander Fleming, fungi have been a treasure trove of medicinal compounds for almost a century.

19 Dec 2024

New Virus Found to Alter Cell Machinery in Eukaryotic Cells

Julie Thomy, lead author of the study and postdoctoral researcher in the Daniel K. Inouye Center for Microbial Oceanography: Research and Education (C-MORE) and Department of Oceanography in the UH Mānoa School of Ocean and Earth Science and Technology (SOEST)

18 Dec 2024