Lab Automation and Bioinformatics News and Research

Latest Lab Automation and Bioinformatics News and Research

OGT Delivers Superior MRD Detection Capabilities with New SureSeq Myeloid MRD Panel

Today, OGT announces the North American launch of its new next-generation sequencing (NGS) SureSeq™ Myeloid MRD Panel, which provides a flexible NGS workflow for the detection of ultra-low frequency measurable residual disease (MRD)-associated biomarkers in acute myeloid leukemia (AML).

23 Jan 2025

Microbiome Signatures Can Predict Nonalcoholic Fatty Liver Disease

Using medical data from more than 1,200 people, specific microbiome signatures have been identified that allow precise prediction of Nonalcoholic Fatty Liver Disease (NAFLD).

22 Jan 2025

Genetic Mutations May Be Behind Epigenetic Clock of Aging

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

22 Jan 2025

Microgravity Unlocks Secrets to Heart Cell Survival for Earth-Based Therapies

A team of researchers led by Emory's Chunhui Xu recently found that heart muscle cells can grow -and survive in the microgravity environment of space.

22 Jan 2025

New Technique Unifies Protein Size Measurements to Predict Aggregation Risk

Proteins are necessary for many bodily processes. Numerous physiological functions and activities are carried out by thousands of distinct proteins.

21 Jan 2025

Mapping Global Microbial Diversity Using Genomic Sequencing Data

Metagenomic datasets could help map out microbial diversity hotspots. Published January 17, 2025 in Science Advances, researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Berkeley Laboratory, have taken stock of the current state of microbial genomic biodiversity.

20 Jan 2025

Bacterial Growth in Mucus Leads to Formation of Cable-Like Structures

Scientists at Caltech and Princeton University have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of "living Jell-O."

20 Jan 2025

Mapping of Neuronal IL-1R1 Expression in the Mouse Brain Sheds Light on Mood and Memory

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.

20 Jan 2025

Unveiling the Interplay of DNA and RNA Epigenetics

The genes contain all the instructions the human body needs to function, but their expression must be carefully regulated to guarantee that each cell performs its function as best it can.

20 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Long Reads Show Promise for Diagnosing Rare Genetic Disorders

The cause of rare diseases is increasingly being detected through genome sequencing, which involves reading the entire human DNA by first breaking it into small pieces-short reads.

16 Jan 2025

New Study Offers Hope for Safer, More Effective Snakebite Treatment

Last year’s Chemistry Nobel Laureate published a new study in Nature that could revolutionize the way snakebite is treated.

16 Jan 2025

EMBL and ELLIS Forge Strategic Partnership to Advance AI in Life Sciences

A new collaborative agreement aims to help position Europe at the forefront of AI-driven advancements in life sciences research.

15 Jan 2025

Genetic Analysis Sheds Light on How Staphylococcus aureus Evades the Immune System

The most detailed study to date on the mechanisms by which a common type of bacterium, Staphylococcus aureus, adapts to living on the human body could help improve the prevention, diagnosis, and treatment of certain infections.

15 Jan 2025

New Genetic Risk Factor Identified for SARS-CoV-2 Infection

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus' ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

15 Jan 2025

Understanding RapA's Function in E. coli R-loop Control

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.

15 Jan 2025

Exploring the Therapeutic Potential of Copper Against Bacteria

A researcher at the University of Arizona College of Medicine in Tucson was awarded a $1.9 million grant by the National Institutes of Health to carry out more research on the mysteries of copper, particularly how it can be used to eradicate dangerous bacteria and other microorganisms.

13 Jan 2025

Outer Ears Evolved From Fish Gills Through Unique Genetic Mechanism

The outer ear is unique to mammals, but its evolutionary origin has remained a mystery. According to a new study published in Nature from the USC Stem Cell lab of Gage Crump, this intricate coil of cartilage has a surprisingly ancient origin in the gills of fishes and marine invertebrates.

10 Jan 2025

Neuropilin2 Gene Disruption Impacts Brain Circuitry in Autism and Epilepsy

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

10 Jan 2025