Microscopy News and Research

Latest Microscopy News and Research

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

3 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

It is still unclear how antibiotics work to destroy bacteria. This knowledge, however, is required for the development of new antibiotics. That is exactly what is required because bacteria are becoming increasingly resistant to existing antibiotics.

27 Mar 2023

Effective encoding strategy streamlines the handling and storage of single-cell data

Single-cell analysis is an effective biomedical technique used to identify unusual cell populations, monitor cell development and differentiation, comprehend disease causes, and design individualized therapies, but it generates massive amounts of data that can be challenging to handle.

23 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

16 Mar 2023

First molecular images of olfaction sets the stage to create novel smells

Breaking a longstanding impasse in our understanding of olfaction, scientists at UC San Francisco (UCSF) have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.

16 Mar 2023

Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

Documenting the lithiation process in TEM can provide a deep understanding of the electrode degradation mechanism during battery cycling, which enhances material modification for improved performance. The research was guided by Prof. Dong Su (Institute of Physics, Chinese Academy of Sciences).

15 Mar 2023

New perspective on how immune cells perceive viruses and other threats

A textbook chapter on the immune system may need to be revised as a result of a new study from Aarhus University.

14 Mar 2023

Neural-network-based image recognition models for examining SCC defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with microscopy images of individual stained chromosomes, identified by researchers as having or not having cohesion defects. After training, it was able to successfully classify 73.1% of new images. Automation promises better statistics, and more insight into the wide range of disorders which cause cohesion defects.

14 Mar 2023

Analyzing microscopic chalk disks coccoliths formed by the marine algae

Under the guidance of Rutgers University, a research group learning about virus-host interactions of worldwide abundant and armor-plated marine algae, Emiliania huxleyi, has discovered that the circular and chalk plates produced by the algae have the potential to serve as catalysts for viral infection.

From Rutgers University 7 Mar 2023

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

For almost 140 years, the origin and behavior of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery.

3 Mar 2023

Uncovering the complete 3D structure of p53 protein

By inducing cell repair or self-destruction, the tumor suppressor protein p53, often known as “the guardian of the genome,” shields the body’s DNA from daily stress or long-term damage.

2 Mar 2023

Nanosatellite paves the way for developing RNA-based medicines

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

New center offers electron microscope services to the scientific community

The Joint Electron Microscopy Center at ALBA (JEMCA) was established through the collaboration of various research agencies to open a new center within the ALBA Synchrotron building that provides electron microscope assistance to the scientific community.

27 Feb 2023

Microscopy News and Research

Latest Microscopy News and Research

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

The proper implementation of stem cell-based disease models

Determining the structure of protein pumps using cryo-EM

Human cells shed light on basic squid biology

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

Effective encoding strategy streamlines the handling and storage of single-cell data

The protein synthesis mechanism in the Giardia parasite

New antibody "cocktail" may help counter the Lassa virus

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

First molecular images of olfaction sets the stage to create novel smells

Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

New perspective on how immune cells perceive viruses and other threats

Neural-network-based image recognition models for examining SCC defects

Analyzing microscopic chalk disks coccoliths formed by the marine algae

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

Uncovering the complete 3D structure of p53 protein

Nanosatellite paves the way for developing RNA-based medicines

New center offers electron microscope services to the scientific community

Life Science Microscopy eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Microscopy News and Research

Latest Microscopy News and Research

Life Science Microscopy eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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