Microscopy News and Research

Latest Microscopy News and Research

MoBIE: New user-friendly, freely available tool for sharing large imaging data sets

High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data.

24 Feb 2023

Thrive Bioscience launches new CellAssist family product capabilities to advance live cell imaging

Thrive Bioscience Inc., an innovative provider of automated live cell imaging instruments and software, debuts a new integrated suite of unique and exciting capabilities that significantly advance the field of live cell imaging.

24 Feb 2023

Realistic model explores new treatments for brain tumors

Until now, the use of models to study the barrier that differentiates the circulatory and nervous systems has been either limited or extremely complex. ETH Zurich researchers have created a more accurate model that can also be used to effectively investigate new treatments for brain tumors.

21 Feb 2023

Accelerating the structure-guided discovery of chemogenetic tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells. One way is by using a tool called DREADDs, which stands for Designer Receptors Activated by Designer Drugs.

21 Feb 2023

Tracking cell movement across time and space using AI

The huge amount of data achieved by filming biological processes with the help of a microscope has earlier been a hindrance to analyses.

17 Feb 2023

New method for studying mitochondria using advanced imaging technology

Scientists at Scripps Research have developed an advanced imaging-based approach that provides a unique perspective on mitochondria, which are best known as the “powerhouses” of cells.

17 Feb 2023

New method triggers and analyzes the dynamics of brain protein linked to Alzheimer’s

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

3D structure of a major protein complex in cilia revealed

Researchers at St. Jude Children’s Research Hospital have solved the 3D structure of an important protein complex in cilia, which are signaling appendages found on cells. The structure was pictured at the highest resolution available at the time.

15 Feb 2023

Fiber optical nanomechanical probe can measure in vivo biomechanical properties of tissue, single cell

Fiber sensing scientists at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) for measuring in vivo biomechanical properties of tissue and even single cell.

13 Feb 2023

Technology development could help expand usefulness of Raman microscopy

Researchers have developed a Raman microscope that can acquire information hundreds of times faster than a conventional Raman microscope.

8 Feb 2023

Gaining insights into human disease biology through CRISPR platforms

In this interview, we speak with Laralynne Przybyla about how she is utilizing CRISPR platforms to understand human disease biology in greater detail.

From Society for Laboratory Automation and Screening (SLAS) 7 Feb 2023

Study elucidates the structure of centromeric region in chicken cells

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

7 Feb 2023

Structure of amyloid fibers formed by the protein hnRNPDL-2 determined

Using high-resolution cryo-electron microscopy (cryo-EM), UAB researchers determined the structure of amyloid fibers formed by the protein hnRNPDL-2, which has been linked to limb-girdle muscular dystrophy type 3 and concluded that the protein’s inability to form amyloid ﬁbers, rather than aggregation, would be the cause of the disease.

6 Feb 2023

Countering climate change with nanowires produced by bacteria

Rapid climate change poses a serious and immediate threat to life on Earth. As atmospheric methane traps heat 30 times more effectively than CO2, temperatures are rising as a result.

3 Feb 2023

RNA-G quadruplexes in living cells: A real-time study

Amyotrophic lateral sclerosis (ALS), sometimes referred to as Stephen Hawking’s disease and Lou Gehrig’s disease is a neurological condition that causes the body’s muscles to gradually lose control.

2 Feb 2023

Proteins’ movement and the spread of antibiotic resistance

Umeå University researchers have figured out how a particular type of protein travels during DNA replication. The discovery could affect the current understanding of how bacteria propagate antibiotic resistance genes.

30 Jan 2023

Cryo-EM helps visualize the detailed structure of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

30 Jan 2023

A 3D explanation of SPOP’s role in cancer

The protein SPOP, which also plays a role in endometrial, uterine, and other cancers, is the most mutated in prostate cancer. Despite its significance, it is still unclear how SPOP mutations cause cancer.

26 Jan 2023

Highly potent antibiotic candidate identified

One of the most promising new antibiotic candidates in decades is a powerful plant toxin that harbors a novel way of killing hazardous bacteria.

26 Jan 2023

New insights into cell health and disease

Scientists from Weill Cornell Medicine have discovered a protein that not only prepares DNA for replication but also controls the replication process. The research, which was published on January 5th, 2023, in the journal Molecular Cell, resolves a puzzle that has long-baffled biologists.

26 Jan 2023