Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Experts analyze key protein complexes involved in DNA replication and repair

Cryogenic electron microscopy (cryo-EM) allows scientists to investigate the assembly of DNA replication machinery where DNA is damaged.

25 Nov 2021

Regulating the activity of a protein enhances health span, says research

Scientists from KAIST put forth novel insights for enhancing the health span by controlling a protein’s activity.

25 Nov 2021

Study identifies key proteins that damage skin cells in psoriasis

Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.

25 Nov 2021

Viral RNA undergoes conformational changes to hijack host cells, says study

Scientists from the University of Colorado Anschutz Medical Campus recently identified how an RNA molecule from a virus develops a complex, three-dimensional structure, and is capable of changing its shape to hijack host proteins.

25 Nov 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

UD biochemist explores how mRNA eraser enzymes work in our cells

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how science can pave the way for possible solutions to this problem.

25 Nov 2021

Study shows why disruption of the body clock leads to inflammatory diseases

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

25 Nov 2021

Study unravels how plants respond differently to useful and harmful microbes

Plants interact with a diversity of organisms over the course of their lifetime, but even very similar microbes can cause opposite reactions.

24 Nov 2021

New details about Shigella's translocon may help develop effective strategy to block infection

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Research identifies distinct gut bacterial profile highly responsive to IBS dietary therapy

People who respond well to the recommended dietary therapy of restricting intake of fermentable carbs for irritable bowel syndrome, or IBS for short, have an abundance of particular types of bacteria in their gut, reveals research published online in the journal Gut.

23 Nov 2021

Deep learning can generate real insights into how proteins interact

Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.

23 Nov 2021

Researchers expand understanding of how T cells recognize infections or disease

T cells communicate with other cells in the body in search of infections or diseases. This crosstalk relies on specialized receptors known as T cell receptors that recognize foreign molecular fragments from an infection or cancer that are presented for detection by particular molecules called major histocompatibility complex (MHC) or MHC-like.

23 Nov 2021

Scientists develop advanced imaging technique to analyze oxygenation within bone tissue

Without doubt, the future of life sciences is sure to have technology that can measure biological parameters real-time in living organisms.

23 Nov 2021

New technique could dramatically speed up the breeding of new crops

Scientists are a step closer to breeding plants with genes from only one parent. New research led by plant biologists at the University of California, Davis, published Nov. 19 in Science Advances, shows the underlying mechanism behind eliminating half the genome and could make for easier and more rapid breeding of crop plants with desirable traits such as disease resistance.

From The University of California, Davis 22 Nov 2021