Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Elaborating how amino acids shaped the genetic code of ancient microbes

Researchers discovered that without specific amino acids, ancient proteins would not have identified how to evolve into anything alive on the planet today, including plants, animals, and humans, by mimicking early Earth conditions in the lab.

28 Feb 2023

RNA modification plays a vital role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis-the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease-involve the buildup of a protein called TDP-43.

28 Feb 2023

Nanosatellite paves the way for developing RNA-based medicines

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

Researchers show how the production of different macromolecules peaks at different times

Textbooks will tell you that in dividing cells, the production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level.

28 Feb 2023

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.

28 Feb 2023

Study reveals why the FMO5 gene produces an enzyme with a different activity

Our body produces lots of enzymes that break down toxic substances. One class of such enzymes are the flavin-containing monooxygenases (FMOs), which are present in all tetrapods. Humans have five different FMO genes, of which the first four display the same activity. However, the fifth FMO gene triggers a different breakdown reaction. University of Groningen biochemists have succeeded in resurrecting the ancestral genes of all tetrapod FMOs to show how this divergence has occurred. Their results appear on 24 February in Nature Communications.

28 Feb 2023

New center offers electron microscope services to the scientific community

The Joint Electron Microscopy Center at ALBA (JEMCA) was established through the collaboration of various research agencies to open a new center within the ALBA Synchrotron building that provides electron microscope assistance to the scientific community.

27 Feb 2023

Artificial BBB model can help determine how well antibody-based therapies can enter the brain

A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.

27 Feb 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Insilico Medicine, a clinical-stage biotech company powered by generative AI, today announces that China National Medical Products Administration (NMPA) has approved the Investigational New Drug (IND) application for ISM3312, an orally available 3CLpro inhibitor generated and designed with the support of Insilico's proprietary generative chemistry platform Chemistry42 for the treatment of COVID-19.

24 Feb 2023

Researchers tease apart the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

24 Feb 2023

Scientists receive $2.5 million NIH grant to define the role of lipid droplets in muscle stem cell function

A team of Purdue University scientists led by Shihuan Kuang has received a $2.5 million grant from the National Institutes of Health to define the role of lipid droplets in muscle stem cell function, a study with implications in both humans and livestock.

24 Feb 2023

Using ultrasound waves to move genetically engineered cells

Let's say you needed to move an individual cell from one place to another. How would you do it? Maybe some special tweezers? A really tiny shovel?

24 Feb 2023

New genetic research could make growing wheat in drought conditions easier in future

Growing wheat in drought conditions may be easier in the future, thanks to new genetic research out of the University of California, Davis.

24 Feb 2023

Whole genome sequencing might help better assess tumor evolution

To develop the most efficacious, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, researchers and clinicians must first understand the genetic changes that cause cancer to develop.

23 Feb 2023

Robust method for induced pluripotent stem cell culture

Different types of cells, such as the heart, liver, blood, and sperm cells, have characteristics that help them perform their specific functions in the body. In general, those traits are hard-wired. A heart cell will not randomly transform into a liver cell if not stimulated.

23 Feb 2023

New compound found in cigarette smoke damages human lung cells’ DNA

Once in a while, people are exposed to possibly detrimental substances in the environment or through their habits or diets. For instance, a compound discovered in cigarette and industrial smoke, benzo(a)pyrene (BaP), is responsible to damage DNA.

23 Feb 2023

Artificial intelligence creates proteins to hasten chemical reactions

Scientists have for the first time utilized machine learning to design whole new enzymes, which are proteins that quicken chemical reactions. In the realm of protein design, this is a crucial development since new enzymes can find several applications in both industrial manufacture and medicine.

23 Feb 2023

New model describes the enormous range of DNA in nature

Why neutral sequences, frequently referred to as “junk DNA,” are not removed from the genomes of living things in nature and persist there even millions of years later is a scientific mystery that could have a possible answer according to a new model created at Tel Aviv University.

23 Feb 2023

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

A new Australian study led by SAHMRI and Flinders University has uncovered fundamental differences in how the AstraZeneca and Pfizer COVID-19 vaccines impact the immune system.

23 Feb 2023

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Elaborating how amino acids shaped the genetic code of ancient microbes

RNA modification plays a vital role in TDP-43-related neurodegeneration in ALS

Nanosatellite paves the way for developing RNA-based medicines

Researchers show how the production of different macromolecules peaks at different times

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

Study reveals why the FMO5 gene produces an enzyme with a different activity

New center offers electron microscope services to the scientific community

Artificial BBB model can help determine how well antibody-based therapies can enter the brain

Study shows why a specific gene mutation has opposite effects on mice and human cancers

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Researchers tease apart the molecular components involved in abdominal aneurysms

Scientists receive $2.5 million NIH grant to define the role of lipid droplets in muscle stem cell function

Using ultrasound waves to move genetically engineered cells

New genetic research could make growing wheat in drought conditions easier in future

Whole genome sequencing might help better assess tumor evolution

Robust method for induced pluripotent stem cell culture

New compound found in cigarette smoke damages human lung cells’ DNA

Artificial intelligence creates proteins to hasten chemical reactions

New model describes the enormous range of DNA in nature

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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