Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Engineered Sustainable, Patient-Specific NPCs Could Help Treat Neurodegenerative Diseases

Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson's disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa.

21 Apr 2023

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

People with dementia have protein build-up in astrocytes that may trigger abnormal antiviral activity and memory loss, according to a preclinical study by a team of Weill Cornell Medicine investigators.

21 Apr 2023

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Macrophages in the Duodenum Play an Important Role in Iron Deficiency

Approximately one to two milligrams of the trace element must be supplied daily through food and finally absorbed in the duodenum for a balanced iron metabolism.

21 Apr 2023

Food-Poisoning Bacteria Create Syringe-Like Structures to Inject Toxins Into Intestinal Cells

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

21 Apr 2023

Using Natural Collagen Extracted from Squid as Tissue Scaffold for Growing Cells

Collagen is the basic protein that makes up the intercellular matrix, or in other words, the environment for the connective tissue cells of our body, such as tendons, bone, and cartilage.

21 Apr 2023

Spatial Organization of Chromosomes and the Role of DNA Tension

Two protein complexes are primarily responsible for chromosomal spatial organization in human cell nuclei. DNA tension has an unanticipated function in this. Together with Austrian colleagues, nanoscientist Cees Dekker and his PhD candidate Roman Barth of TU Delft’s Kavli Institute of Nanoscience published their detailed visualization in Nature on April 19th, 2023.

21 Apr 2023

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

Two protein complexes are involved in the mysterious process of shutting off one X chromosome in female mammals, according to a new study from RIKEN. This result could aid in the understanding of how specific tumors in women develop.

21 Apr 2023

Changes in Gut Microbiomes of Astronauts May be Linked to Bone Loss

In space, the bone density of both the human astronauts and rodent variety decreases. Scientists published this study on April 19th, 2023, in the journal Cell Reports. It says that alterations to the gut microbiomes of space travelers may be linked to this bone loss.

21 Apr 2023

Hair-Coloring Stem Cells in the Hair Germ Compartment Trigger Pigmentation

Some stem cells have a special capacity to mobilize among growth compartments in hair follicles; however, they get stuck with age in people. Hence, they lose their capacity to mature and retain hair color, as per new research.

From New York University (NYU) 21 Apr 2023

Using Cellular Reprogramming to Make the Heart Function Like New Again

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

20 Apr 2023

A Previously Unknown Mechanism for DNA Folding Revealed

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

20 Apr 2023

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

20 Apr 2023

Microalgae Grown in the Lab for Producing Biofuel

A group of researchers at the State University of Campinas (UNICAMP) in Brazil have grown microalgae under controlled conditions in a laboratory in order to use their metabolites, especially lipids, with the prime purpose of producing biofuel.

20 Apr 2023

Adding Few Cell Layers Inside a Corn Kernel Could Increase the Grain's Nutrient Content

What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

20 Apr 2023

Researchers Reveal Dual Nature of Beneficial Bacteria UD1022

Alfalfa, also known in Latin as Medicago sativa, is an agricultural crop that is part of the legume family. It is known as a protein-rich food source for dairy cattle that is easily digested and can lead to increased milk production.

19 Apr 2023

Researchers Identify Novel Role of a Protein in the Development of Alcohol-Associated Liver Disease

Alcohol-associated liver disease (ALD), a complex disorder that occurs in some patients who have engaged in excessive alcohol use, is one of the leading causes of chronic liver disease among veterans and liver transplant patients in the United States.

19 Apr 2023

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Engineered Sustainable, Patient-Specific NPCs Could Help Treat Neurodegenerative Diseases

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

Macrophages in the Duodenum Play an Important Role in Iron Deficiency

Food-Poisoning Bacteria Create Syringe-Like Structures to Inject Toxins Into Intestinal Cells

Using Natural Collagen Extracted from Squid as Tissue Scaffold for Growing Cells

Spatial Organization of Chromosomes and the Role of DNA Tension

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

Changes in Gut Microbiomes of Astronauts May be Linked to Bone Loss

Hair-Coloring Stem Cells in the Hair Germ Compartment Trigger Pigmentation

Using Cellular Reprogramming to Make the Heart Function Like New Again

A Previously Unknown Mechanism for DNA Folding Revealed

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

Microalgae Grown in the Lab for Producing Biofuel

Adding Few Cell Layers Inside a Corn Kernel Could Increase the Grain's Nutrient Content

Researchers Reveal Dual Nature of Beneficial Bacteria UD1022

Researchers Identify Novel Role of a Protein in the Development of Alcohol-Associated Liver Disease

A Novel Mechanism Identified for Lower Energy Expenditure After Weight-Loss

Scientists Discover Gene That Plays a Key Role in Determining the Risk for Vascular Diseases

Molecular Mechanisms That Maintain the Tissue Specificity of PKMzeta

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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