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Experimental optimization of prime editing to achieve high efficiency

Genome editing technologies have enormous potential for treating genetic diseases. Techniques like the extensively used CRISPR/Cas9 gene scissors target the source of the disease directly in the DNA.

3 Feb 2023

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Scientists at ISTA show that pathogens are adapting to social health care measures by ants.

3 Feb 2023

Scientists unravel the physics of a cellular process linked to aggregation diseases

Researchers from Princeton University have uncovered the physics of a cellular process linked to aggregation diseases including Huntington's disease, paving the way to a deeper understanding of neurodegenerative disorders at the molecular level.

3 Feb 2023

New chemical reaction could transform drug production

Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production.

3 Feb 2023

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

3 Feb 2023

Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

Brooks Instrument announces new certifications available for its SLA Series of mass flow controllers

Brooks Instrument, a world leader in advanced flow, pressure and vapor delivery solutions, has released three new certifications available for its SLA Series and SLA Series Biotech mass flow controllers (MFCs) and meters, adding to its wide offering of product documentation.

From Brooks Instrument 3 Feb 2023

RNA-G quadruplexes in living cells: A real-time study

Amyotrophic lateral sclerosis (ALS), sometimes referred to as Stephen Hawking’s disease and Lou Gehrig’s disease is a neurological condition that causes the body’s muscles to gradually lose control.

2 Feb 2023

Cancer therapies improved by changing an antibody’s binding to a target

Before World Cancer Day (4th February), new research from the Centre for Cancer Immunology at the University of Southampton has demonstrated that altering how firmly an antibody attaches to a target can enhance cancer treatments.

2 Feb 2023

Easy-to-use method quantifies exosomal miRNAs

Most cancer diagnostic procedures, like endoscopies, biopsies, and mammograms, are stressful and invasive. Although blood samples may be a less unpleasant option, only a few forms of the disease can as of now be diagnosed this way.

2 Feb 2023

Automatic sample pretreatment microsystem operates through speech recognition

People use smart voice assistants to get quick answers or to play their favorite music. This same technology has the potential to make laboratories safer for scientists and technicians who work with potentially infectious samples.

2 Feb 2023

Scientists define four cancer molecular subtypes using PDX models

Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths.

2 Feb 2023

Extra nitrogen from fuel pollution causes dry soil to let go of carbon

New UC Riverside research suggests nitrogen released by gas-powered machines causes dry soil to let go of carbon and release it back into the atmosphere, where it can contribute to climate change.

2 Feb 2023

Addressing consumer-perceived gastrointestinal effects associated with fiber-rich diets

When enhancing foods to capture the health-promoting benefits of non-digestible carbohydrates like fiber, it is important to address consumer-perceived gastrointestinal effects typically associated with fiber-rich diets.

2 Feb 2023

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

It's almost Valentine's Day, and love is in the air. Or in the waxy coating on your skin, if you are a vinegar fly. That's where flies encounter pheromones that play an important role in regulating sexual attraction.

1 Feb 2023

Exploring how plants can adapt to accelerating aridity due to climate change

At a time when climate change is making many areas of the planet hotter and drier, it's sobering to think that deserts are relatively new biomes that have grown considerably over the past 30 million years.

1 Feb 2023

Microbiome therapeutic linked to quality of life improvement in patients with recurrent C. diff infection

Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).

1 Feb 2023

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

When we try walking in a straight line with our eyes closed, after a few steps forward we inevitably deviate from our intended path.

1 Feb 2023

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

A genetic mutation in the SPTSSA gene is identified as the cause of Hereditary Spastic Paraplegia, a rare disease that causes progressive weakness, stiffness and spasticity in the lower extremities, according to a study, "SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia," published in Brain on on Jan. 30.

1 Feb 2023

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity."

1 Feb 2023

Life Science News

Experimental optimization of prime editing to achieve high efficiency

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Scientists unravel the physics of a cellular process linked to aggregation diseases

New chemical reaction could transform drug production

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Researchers establish and characterize a stable iPSC line for modeling human disease

Brooks Instrument announces new certifications available for its SLA Series of mass flow controllers

RNA-G quadruplexes in living cells: A real-time study

Cancer therapies improved by changing an antibody’s binding to a target

Easy-to-use method quantifies exosomal miRNAs

Automatic sample pretreatment microsystem operates through speech recognition

Scientists define four cancer molecular subtypes using PDX models

Extra nitrogen from fuel pollution causes dry soil to let go of carbon

Addressing consumer-perceived gastrointestinal effects associated with fiber-rich diets

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

Exploring how plants can adapt to accelerating aridity due to climate change

Microbiome therapeutic linked to quality of life improvement in patients with recurrent C. diff infection

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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