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Scientists Decode ApoB100 Structure for Targeted Heart Disease Treatments

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

4 Feb 2025

Omega-3 Slows Aging at the DNA Level, Vitamin D and Exercise Boost the Effect

A clinical trial found that omega-3 supplementation modestly slowed biological aging, with additional benefits when combined with vitamin D and exercise.

4 Feb 2025

Researchers Uncover CAR Molecule Transfer Mechanism

Engineered immune cells known as CAR-T cells are utilized in cancer treatment. Researchers at Uppsala University have recently identified that CAR molecules can be transferred from CAR-T cells to other T cells within the tumor microenvironment.

4 Feb 2025

Exploring Chromatin's Resilience to Develop Anti-Aging Strategies

The process of aging in the body may be more resilient than previously believed, according to a new study.

4 Feb 2025

New Microscopy Technique Reveals Cancer's Metabolic Secrets

Understanding how tumors alter their metabolism to evade treatments is an increasingly important area of cancer research.

4 Feb 2025

Grasshopper Populations Reveal Winners and Losers of Climate Change

As insect populations decrease worldwide in what some have called an "insect apocalypse," biologists are desperate to determine how the six-legged creatures are responding to a warming world and to predict the long-term winners and losers.

3 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

Generative AI Decodes the 3D Structure of DNA

Although the genetic sequence is the same in every cell in the body, only a subset of those genes is expressed by each cell.

3 Feb 2025

New Insights into Akkermansia's Role in Gut Health

A microbe found in the lower part of the gut, linked to good health, has been thoroughly analyzed and found to specialize in breaking down sugars hidden in mucus as part of its focused diet.

3 Feb 2025

Microscopy Technique Tracks Ribosome Activity

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

3 Feb 2025

Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology, transforming protein engineering.

3 Feb 2025

The Cost of Being King: Alpha Baboons Trade Power for Survival

Research on male baboons reveals that alpha males face higher energetic costs and chronic stress, challenging assumptions about dominance and well-being.

3 Feb 2025

Danish Protein Analysis to Revolutionize the Biopharma Industry’s Impurity Control

Since 2007, the contract laboratory Alphalyse A/S has developed and refined a new method of impurity analysis in biological pharmaceuticals based on mass spectrometry (MS).

3 Feb 2025

Random Versions of Human Genomes Created to Unlock Disease Mechanisms

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

3 Feb 2025

Understanding How α2δ Protein Mutations Influence Brain Development in Autism

A recent study has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the proteins’ membrane expression and synaptic targeting but do not impair calcium channel activity or trans-synaptic signalling.

3 Feb 2025

New Method Helps Detect Mutations Causing Immune Escape in Viruses

Viruses are masters at disguise. When they are pushed too far by our immune system, they send new virus variants into play that are no longer recognized by immune cells.

31 Jan 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

Researchers Uncover How Fruit Flies Taste Food Texture

A study led by Nikita Komarov and Simon Sprecher at the University of Fribourg, Switzerland, has discovered neurons in the fly larva mouth that allow the taste of food texture.

31 Jan 2025

Research Paves Way for Off-the-Shelf CAR T Cells for Cancer Treatment

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Studies Reveal Early Resistance to Newly Developed Antibiotics

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics. Two recent studies, published just days apart in Nature Microbiology and Science Translational Medicine found that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.

31 Jan 2025