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Human Cell Lines Reveal Genome's Tolerance to Structural Variation

The most advanced engineering of human cell lines to date has been accomplished by scientists, demonstrating that genomes are more robust against significant structural changes than previously understood.

31 Jan 2025

Novel Chemo-Optogenetic Systems Offer Spatiotemporal Precision

A research team at Umeå University has created advanced light-controlled tools that allow for precise regulation of proteins in real time within living cells.

31 Jan 2025

EpiBERT AI Model Reveals How Genes Are Regulated in Human Cells

A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can predict which genes are expressed in any type of human cell.

30 Jan 2025

Durham University Researchers Unveil Tool to Predict Protein Metalation

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life.

30 Jan 2025

Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

Coffee's Bitter Taste Linked to Genetics and Roasting Process

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

30 Jan 2025

New Microfluidic Device can Detect SARS-Cov-2 with Revolutionary Sensitivity

VirusHB-Chip offers groundbreaking sensitivity in detecting SARS-CoV-2 in plasma, saliva, and stool, transforming COVID-19 diagnostics and treatment strategies.

30 Jan 2025

Leveraging AI to Aid the Development of T Cell Vaccine Candidates

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates.

29 Jan 2025

Researchers Apply Advanced AI Genetics Models to Study Parkinson's Disease

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

29 Jan 2025

New Numbering System Advances Adhesion GPCR Research

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies.

29 Jan 2025

High-Throughput Method Reveals the Effects of Active Substances on Cellular Metabolism

Researchers at the University of Basel are able to test in parallel the effects of over 1500 active substances on cell metabolism.

29 Jan 2025

Scientists Create First Healthy Mice with Two Fathers

A group of stem cell researchers has successfully engineered embryonic stem cells to create a bi-paternal mouse, a mouse with two male parents, that survived to adulthood.

29 Jan 2025

New Lipids Dramatically Improve Gene Therapy and Vaccine Delivery

Every time a shuttle docks with the International Space Station (ISS), a precise and intricate process takes place between the shuttle’s docking system and its counterpart on the station

29 Jan 2025

Unraveling the Role of Cyclin B Docking in Regulating Cell Division

Cell division is essential for the survival of all living organisms, from the simplest yeast to complex human beings.

29 Jan 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

New Method Helps T Cells Live Longer and Fight Cancer More Effectively

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

29 Jan 2025

Unique Genetic Signature Predicts Bacteria's Potential to Develop Antibiotic Resistance

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually.

29 Jan 2025

Researchers Complete Synthetic Yeast Chromosome, Advancing Genome Engineering

This study details the design and optimization of synXVI, a synthetic yeast chromosome, overcoming growth challenges through innovative genomic strategies.

29 Jan 2025

Genome Analysis Reveals How Giant Clams Evolved to Coexist with Algae

Giant clams, some of the largest mollusks on Earth, have long fascinated scientists. These impressive creatures can grow up to 4.5 feet in length and weigh over 700 pounds, making them icons of tropical coral reefs.

28 Jan 2025

New Epigenetic Tool Can Track Androgen Exposure Over Time

Researchers from the University of Otago – Ōtākou Whakaihu Waka have created a world-first epigenetic tool which has implications for medicine, sports, and agriculture.

28 Jan 2025