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New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Largest study identifies causal genetic variants associated with type 1 diabetes risk

Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

Natto, a Japanese fermented soybean dish, may hold the key to COVID-19 treatment

Natto is a fermented soybean dish usually served by the Japanese for breakfast. Although it actually originated at the turn of the last millennium, it could be the key to a modern problem—COVID-19—reports a new cell-culture-based study.

23 Jul 2021

Researchers successfully create genetically engineered marsupials via genome editing

Scientists from the RIKEN Center for Biosystems Dynamics Research (BDR) successfully created the first genetically engineered marsupial. The research and its findings published in the Current Biology journal help decipher the genetic background of special characteristics found only in marsupials.

23 Jul 2021

Research identifies vitamin C as a key ingredient for immune cell function

A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.

23 Jul 2021

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.

22 Jul 2021

New study uncovers how enterococcal cytolysins affect cells

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so.

22 Jul 2021

Soil microbes are critical players in corn heterosis

The tiny organisms living in soil may have a greater effect on the yield and pest and disease resistance of crop plants grown in that soil than previously known.

22 Jul 2021

Toward an antiviral drug that works against all coronaviruses

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.

22 Jul 2021

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors).

22 Jul 2021

New test to detect substances that are harmful to the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

Cell couriers offer clue to how cancers metastasize into secondary tumors

A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University of Warwick.

From The University of Warwick 22 Jul 2021

L452R mutation of SARS-CoV-2 spike protein is involved in cellular immunity evasion

A research team has demonstrated that the L452R mutation of the SARS-CoV-2 spike protein plays a role in cellular immunity evasion.

21 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021

Study discloses the role of gene cluster variants in producing climate-specific natural substances

Natural substances are of much interest to scientists mainly as the basis for medicines, as some natural substances exhibit interesting properties.

21 Jul 2021

Study unravels gene expression control mechanism with immunity and cancer implications

Despite alternative polyadenylation (APA) affecting a larger part of human genes, the importance of APA was not well understood.

21 Jul 2021

Enzymatic PET recycling has sizeable energy and carbon-saving benefits

Researchers in the BOTTLE Consortium, including from the U.S. Department of Energy's National Renewable Energy Laboratory and the University of Portsmouth, have identified using enzymes as a more sustainable approach for recycling polyethylene terephthalate (PET), a common plastic in single-use beverage bottles, clothing, and food packaging that are becoming increasingly relevant in addressing the environmental challenge of plastic pollution.

21 Jul 2021

Amateur tasters could differentiate among the barley breeding lines in beer

When it comes to craft beer, the flavor doesn't have to be all in the hops. As a panel of amateur beer tasters at Washington State University recently demonstrated, malted barley, the number one ingredient in beer besides water, can have a range of desirable flavors too.

21 Jul 2021

New study evaluates the recovery of DNA from challenging forensic evidence

Duct tape and items retrieved from the water are common pieces of evidence in forensic cases. A new study evaluates the recovery of DNA from folded duct tape that has been submerged in ocean water for up to 2 weeks.

21 Jul 2021

Life Science News

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

Largest study identifies causal genetic variants associated with type 1 diabetes risk

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

Natto, a Japanese fermented soybean dish, may hold the key to COVID-19 treatment

Researchers successfully create genetically engineered marsupials via genome editing

Research identifies vitamin C as a key ingredient for immune cell function

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

New study uncovers how enterococcal cytolysins affect cells

Soil microbes are critical players in corn heterosis

Toward an antiviral drug that works against all coronaviruses

Researchers discover nucleotide sequences characteristic of microRNA isoforms

New test to detect substances that are harmful to the placenta and embryo

Cell couriers offer clue to how cancers metastasize into secondary tumors

L452R mutation of SARS-CoV-2 spike protein is involved in cellular immunity evasion

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study discloses the role of gene cluster variants in producing climate-specific natural substances

Study unravels gene expression control mechanism with immunity and cancer implications

Enzymatic PET recycling has sizeable energy and carbon-saving benefits

Amateur tasters could differentiate among the barley breeding lines in beer

New study evaluates the recovery of DNA from challenging forensic evidence

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