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Review: Role of Alternative Splicing Defects in Major Neurodegenerative Diseases

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -; single-stranded RNAs involved in protein synthesis -; and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Study Links Timing of Childhood Adversity With Epigenetic Patterns in Adolescents

Childhood adversity-;circumstances that threaten to a child's physical or psychological well-being--has long been associated with poorer physical and mental health throughout life, such as greater risks of developing cardiac disease, cancer, or depression.

14 Jun 2023

Achieving 3D Printing Inside 'Mini-Organs' Growing in Hydrogels

Scientists from the NIHR Great Ormond Street Hospital Biomedical Research Centre (a collaboration between GOSH and UCL), London, and University of Padova, Italy, have shown for the first time how 3D printing can be achieved inside 'mini-organs' growing in hydrogels -- controlling their shape, activity, and even forcing tissue to grow into 'molds.'

12 Jun 2023

Molecular Rhythms of Malaria Parasites Sync With the Biological Clock of Human Hosts

Health officials warn that drug resistance could wipe out recent progress against malaria, particularly in Africa and southeast Asia.

7 Jun 2023

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

The Francis Crick Institute has discovered three 4,000-year-old British cases of Yersinia pestis, the bacteria that causes the plague—the oldest evidence of the plague in Britain to date. The study was published in Nature Communications.

31 May 2023

IgA Described as "Tuner" in Microbe Interaction Regulation

Throughout the world, IgA deficiency is considered to be the most common primary immune deficiency, but its presentation has continued to confuse researchers and physicians.

29 May 2023

New Insights Into How Genetic Variants Impact Gene Expression

The Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, in collaboration with the University of California San Francisco and Stanford University, has recently published a study that is the largest of its kind to focus on ancestry correlations with biomedical traits.

26 May 2023

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

A previously unknown function for the SWI/SNF chromatin remodeling complex has been revealed by researchers at St. Jude Children’s Research Hospital.

25 May 2023

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

St. Jude Children’s Research Hospital researchers are investigating how a type of transcription factor known as a pioneer transcription factor reaches DNA even when it is tightly wrapped.

25 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

23 May 2023

CSHL Scientists Flip the Script on Autism Genetics

Cold Spring Harbor Laboratory researchers have flipped the script on autism spectrum disorder (ASD) genetics.

23 May 2023

Novel Gene-Editing Strategy Harnesses Unusual Protective Ability to Eliminate HIV-1 Infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

22 May 2023

Machine Learning Reveals Sex-Specific Genes, Molecular Pathways Linked to Alzheimer's Disease Progression

Alzheimer's Disease (AD) is a complex neurodegenerative illness with genetic and environmental origins.

22 May 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

In Europe, Clostridioides difficile infection results in severe diarrhea and leads to the death of around 20,000 patients, every year. It is one of the most common hospital-acquired infections.

16 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Despite the astounding advances made in understanding the biologic underpinnings of cancer, many cancers are missing obvious genetic drivers.

5 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Children News and Research

Review: Role of Alternative Splicing Defects in Major Neurodegenerative Diseases

Study Links Timing of Childhood Adversity With Epigenetic Patterns in Adolescents

Achieving 3D Printing Inside 'Mini-Organs' Growing in Hydrogels

Molecular Rhythms of Malaria Parasites Sync With the Biological Clock of Human Hosts

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

IgA Described as "Tuner" in Microbe Interaction Regulation

New Insights Into How Genetic Variants Impact Gene Expression

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

CSHL Scientists Flip the Script on Autism Genetics

Novel Gene-Editing Strategy Harnesses Unusual Protective Ability to Eliminate HIV-1 Infection

Machine Learning Reveals Sex-Specific Genes, Molecular Pathways Linked to Alzheimer's Disease Progression

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Innate Tumor Suppression Mechanism Uncovered

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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