Neurodegenerative Diseases News and Research

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Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

NYU Tandon professors show broad therapeutic potential of novel peptide to combat multiple diseases

NYU Tandon professors Mary Cowman and Jin Ryoun Kim recently published a paper describing a novel peptide with broad therapeutic potential to combat chronic inflammation in multiple diseases.

From New York University (NYU) 31 Aug 2021

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

Study identifies C9orf72 repeat expansion using novel genetic marker

Research offers a new genetic tool to pinpoint C9orf72 repeat expansion-carrying frontotemporal lobar degeneration from huge population-based cohorts.

25 Aug 2021

New mouse line reveals the state of proteostasis in mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Novel genome-editing technology to mitigate Alzheimer’s disease

Around 500,000 patients in China alone are considered to be living with a hereditary form of Alzheimer’s disease (AD).

19 Aug 2021

Novel technique quantifies protein droplets involved in neurodegenerative diseases

Some proteins in cells can separate into small droplets like oil droplets in water, but faults in this process may underlie neurodegenerative diseases in the brains of older people. Now, Rutgers researchers have developed a new method to quantify protein droplets involved in these diseases.

16 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for neurodegenerative diseases

Scientists have found that the brain lacks the ability to maintain the cholesterol-rich myelin sheath that insulates neurons when a protein is absent.

From National University of Singapore (NUS) 10 Aug 2021

Muscle protein tied to physical fitness in youth and age-associated diseases

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

9 Aug 2021

New study could help develop novel treatments for neurodegenerative diseases

Researchers have introduced a novel gene therapy program that could set the stage for new treatments for neurodegenerative diseases.

2 Aug 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Study reveals the basis of oxygenation fluctuations in brain

The brain is supplied with sufficient nutrients and oxygen due to the blood flow; however, the oxygenation is likely to fluctuate distinctly and uniformly.

From Penn State University 19 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Study reveals the relationship between gut microbiome and neurodegenerative disorders

Eran Blacher bagged the NOSTER & Science Microbiome Prize 2021 for his work in highlighting the relationship between the microbiome and neurodegenerative diseases.

12 Jul 2021

Experimental model reveals the protective role of antioxidants in neurodegenerative disorders

Researchers used a model to replicate the blood-brain barrier and successfully demonstrated how antibody guards the brain against inflammation.

2 Jul 2021

Genetic treatment may provide a new approach to addressing obsessive-compulsive disorder (OCD)

For the first time, scientists have linked distinct patterns of genetic mutations with OCD in humans using genome-wide analysis.

29 Jun 2021

Specific chemical feature of a key protein may lead to neurodegenerative diseases

Scientists have found that a particular chemical feature of a crucial protein may cause it to build up in the brain and lead to various disorders.

28 Jun 2021

Novel protein interactions aid in the recovery process of brain damage

Patients suffering from brain damage largely depend on rehabilitation therapy for recovery, because no other effective treatment options are available.

21 Jun 2021

New types of glial cells in the brain may treat neurodegenerative diseases

Researchers from the University of Basel have discovered two types of glial cells that may play an important role in brain plasticity and repair.

15 Jun 2021

Study reveals key molecule involved in myelin repair

New research works indicate that new brain cells are continuously formed in response to physical exercise, injury, and mental stimulation.

9 Jun 2021