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Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Researchers aim to tackle neurodegenerative diseases of the eye and brain

Could a new paradigm in digital health treat blinding disorders and possibly also be a conduit for treating other parts of the brain? A multi-disciplinary team of world-renowned researchers at USC are exploring this exciting possibility.

31 Jan 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

From Institut Pasteur 10 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.

4 Jan 2022

Research highlights opportunities to expand the manufacture of stem cells in space

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

3 Jan 2022

INTEGRA supports groundbreaking brain tumor research

INTEGRA Biosciences is proud to be supporting vital translational research into diffuse intrinsic ponsglioma (DIPG) – a rare childhood brain tumor – at the Ludwig Maximilian University of Munich (LMU) with a festive donation of 20,000 EUR.

From INTEGRA Biosciences 21 Dec 2021

Novel peptide vaccine alleviates conditions of dyslipidemia

Professor Yuichi Oike and his group of researchers recently produced a peptide vaccine that mitigates conditions of dyslipidemia.

17 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

8 Dec 2021

Researchers identify protein that promotes wound healing and repair

Recent research discovered a protein known as Agrin that is known to promote wound healing and repair when induced after the injury of skin tissue.

8 Dec 2021

Experts create world’s first single-cell atlas of human and porcine eyes

Researchers recently constructed the first single-cell atlas of the human and porcine eyes.

8 Dec 2021

Cancer drug effective against Alzheimer’s disease, says research

According to recent research carried out by researchers from the Weill Cornell Medicine, a gene mutation associated with Alzheimer’s disease changes a signaling pathway in specific immune cells of individuals with the disease.

7 Dec 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

New technique anticipated to deliver personalized immunotherapies for cancer

Recent research led to a very effective technique to create many immune cells particularly engineered to identify neoantigens.

17 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Experts determine the molecular structure of a gut protein

Researchers from EMBL Hamburg and the Centre for Structural Systems Biology (CSSB) identified the molecular structure of a gut protein that aids the absorption of various drugs. This finding can help produce drugs that reach target tissues more effectively.

8 Nov 2021

Preclinical News and Research

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Researchers aim to tackle neurodegenerative diseases of the eye and brain

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

Novel delivery system for genome editing in vascular endothelial cells developed

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Research highlights opportunities to expand the manufacture of stem cells in space

INTEGRA supports groundbreaking brain tumor research

Novel peptide vaccine alleviates conditions of dyslipidemia

Infant's immune system may be better than the adult immune system

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

Researchers identify protein that promotes wound healing and repair

Experts create world’s first single-cell atlas of human and porcine eyes

Cancer drug effective against Alzheimer’s disease, says research

Treatment with common allergy medication linked to improved immunotherapy response

New technique anticipated to deliver personalized immunotherapies for cancer

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Experts determine the molecular structure of a gut protein

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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