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Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Researchers have explored the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, and breast cancer.

31 Jan 2022

Novel technology combats cancer more quickly and efficiently

Researchers have created a new technology that allows them to use immune cells from tumors to combat cancer more quickly and efficiently.

31 Jan 2022

Researchers catalog the complete cells that form the blood vessels of the human brain

Researchers at UC San Francisco have cataloged all of the cells that make up the blood vessels in the human brain, as well as their positions and the genes produced.

31 Jan 2022

Scientists discover families of proteins that could predict organ transplant rejection

Northwestern University scientists have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care.

28 Jan 2022

IL-6 regulates cartilage regeneration in joints and growth plates, says study

The IL-6 protein family has a poor reputation for promoting inflammation, arthritis, autoimmune disease, and even cancer.

20 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Heart disease continues to be a leading cause of mortality and morbidity across the globe. Positron emission tomography (PET) has slowly become a remarkable technology of a non-invasive technique for accurately diagnosing cardiac diseases.

11 Jan 2022

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

Research team grows mini-stomach across varying stages of development

A group of researchers led from Great Ormond Street Hospital (GOSH) hinged on recent progress to culture “mini-organs” in a lab, called organoids.

From University College London 7 Dec 2021

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

A novel therapeutic approach inhibits the growth of metastatic tumors in mice by coercing cancer cells into a dormant state—where they cannot proliferate.

25 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Surgery News and Research

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Living human breast milk cells offer insight into pregnancy, lactation, and breast cancer

Novel technology combats cancer more quickly and efficiently

Researchers catalog the complete cells that form the blood vessels of the human brain

Scientists discover families of proteins that could predict organ transplant rejection

IL-6 regulates cartilage regeneration in joints and growth plates, says study

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Changes in the activity of gene networks may explain arteriosclerosis risk

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Infant's immune system may be better than the adult immune system

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

New technology can help detect the activity of CRISPR gene editing tools

Researchers regenerate cartilage using novel protein fragment

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

Research team grows mini-stomach across varying stages of development

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

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