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Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Lungs' immune cells can be activated more easily than previously thought

A significant site of damage during COVID-19 infection is the lungs. Understanding how the lungs' immune cells are responding to viral infections could help scientists develop a vaccine.

12 Jun 2020

Researchers identify genes involved in the development of malignant brain tumor

Researchers have developed a new approach to identify functional mutations and their impact on genes applicable to the development of malignant brain tumors.

10 Jun 2020

High sodium intake affects health of gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

10 Jun 2020

RDP1 gene regulates the production of pollen grains

An international study has discovered a gene in the plant model Arabidopsis that reduces the number of pollen grains.

9 Jun 2020

Study reveals the relationship between genome folding and cellular functions

According to a study, the 3D structure of the human genome is fundamental to provide a quick and strong inflammatory response.

9 Jun 2020

Researchers identify a promising biomarker to screen stem cell quality

Published recently in the Stem Cells journal, a new study addresses a major issue that has been challenging the human mesenchymal stem cells (hMSCs) therapy.

9 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

TU Dresden study uncovers enzyme essential for intestinal epithelial differentiation

The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota.

9 Jun 2020

DNA damage and repair jointly shape mutational signatures

A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science, and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute, and the Wellcome Sanger Institute have screened almost 163,000 DNA mutations in 2,700 C. elegans roundworms to shed light on DNA damage.

9 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

Improved RACE-Seq technique helps sequence individual cells

China-based researchers have developed an improved technology that makes it slightly easier to understand cells.

8 Jun 2020

A synthetic microbial system can determine location of origin for objects

Every year, an estimated 48 million Americans get sick from foodborne illnesses, resulting in some 128,000 hospitalizations and 3,000 deaths, according to the U.S. Centers for Disease Control and Prevention.

5 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020

New model decodes relationship between metabolic mechanisms and genes

New research introduces a unique mathematical method to study human metabolism by decreasing the complexities of the human genome-scale GEMs.

5 Jun 2020

C19ORF57 gene could advance reproductive medicine

The gene C19ORF57 has been identified to play a major role in meiosis by the Institute of Molecular Embryology and Genetics at Kumamoto University.

5 Jun 2020

Human protein plays crucial role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome.

5 Jun 2020

Exploring the cradle of hematopoietic stem cells

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

5 Jun 2020

Scientists aim to develop a gene-targeting, antiviral agent to combat COVID-19

A team of scientists from Stanford University is working with researchers at the Molecular Foundry, a nanoscience user facility located at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), to develop a gene-targeting, antiviral agent against COVID-19.

5 Jun 2020