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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Researchers find a sour receptor conserved from fruit flies to humans

Humans and fruit flies respond to many of the same tastes -; sweet, salty, bitter and so on. The receptors that identify these substances, however, are very different between us and insects. Except when it comes to sour.

14 Dec 2021

A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health University, Japan, in collaboration with European research groups, have provided an answer to this question in a new article in PNAS.

14 Dec 2021

Study suggests dietary intake of flavan-3-ols could help prevent obesity

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

14 Dec 2021

Study reveals the biochemistry of long-term memory consolidation

Scientists from Tokyo Metropolitan University recently gained a deeper understanding of the biochemistry of long-term memory.

14 Dec 2021

Research reveals nutrient responses underpinning a potentially deadly, low-chlorophyll state in plants

Green is a color that is almost universally associated with plants-;for good reason. The green pigment chlorophyll is essential to plants' ability to generate food; but what happens if they don't have enough of it?

13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

Experts grow novel cell lines in a chemically defined medium

Researchers for the first time acquired stem cells from livestock that was grown under chemically defined conditions.

13 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

Experts identify subgenome asymmetry at translational level in wheat

Polyploidy is a key route for the creation of new species in plants and a significant means of enhancing agronomic traits in crops.

9 Dec 2021

Study uncovers mechanisms behind rupture and repair of the nuclear envelope

The nucleus present inside the cell is surrounded by the nuclear envelope—two layers of phospholipid membrane that obstructs the nucleus from mixing with other parts of the cell—safeguarding the cell’s DNA from outside damage.

9 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

Study uncovers an immune evasion mechanism of SARS-CoV-2

Scientists discovered that SARS-CoV-2 can knock out a significant molecular pathway associated with an immune complex named MHC class I.

8 Dec 2021

Experts create world’s first single-cell atlas of human and porcine eyes

Researchers recently constructed the first single-cell atlas of the human and porcine eyes.

8 Dec 2021

Cancer drug effective against Alzheimer’s disease, says research

According to recent research carried out by researchers from the Weill Cornell Medicine, a gene mutation associated with Alzheimer’s disease changes a signaling pathway in specific immune cells of individuals with the disease.

7 Dec 2021

Experts identify first non-coding RNA that controls chromosome loop formation

Recent research carried out by scientists from Massachusetts General Hospital (MGH) reveals that a significant player in the healthy development of female embryos also performs a vital role in controlling the behavior of chromosome loops and gene expression in both sexes.

7 Dec 2021