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Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Cellular enlargement drives a decline in function of stem cells, study suggests

MIT biologists have answered an important biological question: Why do cells control their size? Cells of the same type are strikingly uniform in size, while cell size differs between different cell types. This raises the question of whether cell size is important for cellular physiology.

15 Nov 2021

Microbiome differences in autism reflect dietary preferences, says study

Earlier studies suggest that autism spectrum disorder (ASD) might be partly due to differences in the gut microbiota composition.

15 Nov 2021

Study shows how a common gene mutation robs people of natural cancer protection

Scientists from the University of Virginia School of Medicine have identified how a common gene mutation deprives people of natural protection against cancer.

15 Nov 2021

Cellular senescence is caused by irreversible damage to the genome

Researchers have demonstrated that the aging of cells is dependent on a genomic instability mechanism that causes the disease.

15 Nov 2021

New epigenetic editing technique could help treat a wide range of diseases

All the cells found in the body of an individual have the same genetic code.

15 Nov 2021

Mysterious protein clusters found on neurons are calcium-signaling “hotspots”, study reveals

For 30 years, mysterious clusters of proteins found on the cell body of neurons in the hippocampus, a part of the brain, both intrigued and baffled James Trimmer.

From The University of California, Davis 15 Nov 2021

Pacific Ocean rockfish genomes offer new insights into the genetic determinants of aging

Genomes assembled from Pacific Ocean rockfishes – some species of which are among the longest-living vertebrates known – reveal new insights into the genetic determinants of aging.

12 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

Study offers genetic clues on the fundamental development of anatomical appearance

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Whole genome sequencing reveals chickpea's pan-genome

An international team of researchers from 41 organizations has assembled chickpea's pan-genome by sequencing the genomes of 3,366 chickpea lines from 60 countries.

11 Nov 2021

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases.

11 Nov 2021

Research establishes a new understanding of how DNA methylation begins in plants

Crop improvement often involves the transfer of genetic material from one organism to another to produce a valuable trait. Some major examples of crops with these so-called "transgenes" include disease-resistant cotton and beta-carotene-enhanced golden rice.

10 Nov 2021

New program can help to correctly interpret the genetic code of newly sequenced organisms

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

10 Nov 2021

Researchers identify a gene in wheat with profound effects on the production of seeds

Scientists from the John Innes Centre have identified a gene that has deep-rooted effects on seed production in wheat.

10 Nov 2021

Study discusses outcomes of disclosing actionable genetic results to research participants

Over 120,000 patients have enrolled in the Mass General Brigham Biobank, offering access to crucial information related to their health history.

10 Nov 2021

Whole genome sequencing for children with cancer provides accurate diagnosis

According to a new study, revealing the entire genetic code for each child diagnosed with cancer could unravel new treatment options.

10 Nov 2021

Genetic analysis reveals the deep homology between fins and limbs

All vertebrates have the same basic body plan: head, spine, four appendages. Those appendages vary greatly in size, shape, and function, of course -; from fins to wings, arms, and legs -; but a new genetic analysis shows that genes that control development at the ends of the appendages share a deep evolutionary history.

9 Nov 2021

Study sheds light on how genes and air pollution elevate healthy people’s depression risk

A genetic predisposition for depression combined with exposure to high-particulate-matter air pollution greatly elevates the risk that healthy people will experience depression, according to a first-of-its-kind study published today in the Proceedings of the National Academies of Sciences from neuroscientists at the Lieber Institute for Brain Development, on the Johns Hopkins Medical Campus, and Peking University in Beijing, China.

9 Nov 2021

Genetic News and Research

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Cellular enlargement drives a decline in function of stem cells, study suggests

Microbiome differences in autism reflect dietary preferences, says study

Study shows how a common gene mutation robs people of natural cancer protection

Cellular senescence is caused by irreversible damage to the genome

New epigenetic editing technique could help treat a wide range of diseases

Mysterious protein clusters found on neurons are calcium-signaling “hotspots”, study reveals

Pacific Ocean rockfish genomes offer new insights into the genetic determinants of aging

Using a new genetic technology to decipher intratumoral heterogeneity

Study offers genetic clues on the fundamental development of anatomical appearance

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Whole genome sequencing reveals chickpea's pan-genome

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Research establishes a new understanding of how DNA methylation begins in plants

New program can help to correctly interpret the genetic code of newly sequenced organisms

Researchers identify a gene in wheat with profound effects on the production of seeds

Study discusses outcomes of disclosing actionable genetic results to research participants

Whole genome sequencing for children with cancer provides accurate diagnosis

Genetic analysis reveals the deep homology between fins and limbs

Study sheds light on how genes and air pollution elevate healthy people’s depression risk

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