Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Researchers use new decoding method to identify novel proteins encoded by HSV-1

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.

8 Dec 2020

Scientists use advanced methods for investigating structure and interactions of proteins

Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins -- that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules.

8 Dec 2020

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

Researchers design living plant-based sensor to track arsenic levels

For the first time, researchers from SMART have engineered a living plant-based sensor for the detection of arsenic in the belowground environment

3 Dec 2020

Environmental and exogenous compounds can interact with therapeutic drugs, shows study

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

3 Dec 2020

World’s largest proteomics centre accelerates biomarker discoveries to improve people’s lives

Opened in 2016, Manchester’s Stoller Biomarker Discovery Centre (SBDC) is a globally renowned, multi-million-pound precision medicine research facility.

30 Nov 2020

Tau protein in Alzheimer's disease looks different at every dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Astrocytes regulate inhibitory synapses by binding to neurons

In the orchestra of the brain, the firing of each neuron is controlled by two notes--excitatory and inhibitory-- that come from two distinct forms of a cellular structure called synapses.

16 Nov 2020

Study shows how UCH37 enzyme regulates a cell’s waste management system

Researchers reported the discovery of a new enzyme, called UCH37, that controls the waste management system of a cell.

9 Nov 2020

Rapid prognosis of SARS-CoV-2 by MALDI-TOF MS

Gomila et al. recently uploaded a study to the preprint server medRxiv* (November 2020), aiming to utilize MALDI-TOF MS to analyze the sera of patients infected with SARS-CoV-2 in a range of disease severity states.

6 Nov 2020

Innovative machine learning concepts can help develop new drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

15 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

13 Oct 2020

Analysis of wild tomatoes elucidates genetic basis underlying fruit traits

Domestication and subsequent intensive breeding of tomato had a major impact on fruit ripening and the myriad metabolic processes accompanying it.

29 Sep 2020

New study reveals metabolic signature of SARS-CoV-2 infection involving signs of multi-organ damage

SARS-CoV-2 can lead to a broad range of symptoms, from absolutely nothing to multi-organ failure, severe respiratory stress, and eventually death.

11 Sep 2020

Chemical crosslinking data helps study protein dynamics

The mechanism for protein function can be unraveled by defining protein dynamics.

26 Aug 2020

Seafood study finds plastic in all samples

A study of five different seafoods has found traces of plastic in every sample tested.

From University of Exeter 13 Aug 2020

New technology captures common biomarker of heart-disease

Researchers at the University of Wisconsin-Madison have developed a method combining sticky nanoparticles with high-precision protein measurement to capture and analyze a common marker of heart disease to reveal details that were previously inaccessible.

7 Aug 2020

Specific protein found at high levels in the blood of people with early signs of Alzheimer's

Two decades or more before symptoms arise, plaques of a sticky protein called amyloid begin forming in the brains of people later diagnosed with Alzheimer's disease.

29 Jul 2020