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Study holds phages responsible for superbug emergence

Scientists unraveled that phages are responsible for the initiation of rapid bacterial evolution that leads to the rise of treatment-resistant “superbugs.”

From University of Pittsburgh 21 Jul 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

19 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.

19 Jul 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

Study reveals neurotransmitter releases impairments in schizophrenia patients

A research team revealed that neurotransmitter release in the brain is impaired in patients with schizophrenia who possess a rare, single-gene mutation.

16 Jul 2021

Researchers propose replacing ancestry in forensics with a population structure approach

A new study finds forensics researchers use terms related to ancestry and race in inconsistent ways, and calls for the discipline to adopt a new approach to better account for both the fluidity of populations and how historical events have shaped our skeletal characteristics.

15 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Study reveals causal gene in autism model mice with copy number variation

A new study has unraveled a causal gene (Necdin, NDN) in autism model mice that exhibit the chromosomal abnormality known as copy number variation.

13 Jul 2021

Updated Families SHARE workbook helps people use family history to assess disease risk

The Families SHARE workbook was developed by researchers at the NHGRI, which is part of the National Institutes of Health (NIH).

12 Jul 2021

Researchers from Himachal Report a Novel Bacterial Biopigment with Diverse Applications

Researchers have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

9 Jul 2021

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.

8 Jul 2021

New method yields 10 times more accessible details of gene activity in individual cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

7 Jul 2021

Medicine News and Research

Study holds phages responsible for superbug emergence

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

Gene therapy may be safe and effective in treating AADC deficiency

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Study reveals neurotransmitter releases impairments in schizophrenia patients

Researchers propose replacing ancestry in forensics with a population structure approach

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Liver fibrosis might be treatable with selective immunotoxins

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Study reveals causal gene in autism model mice with copy number variation

Updated Families SHARE workbook helps people use family history to assess disease risk

Researchers from Himachal Report a Novel Bacterial Biopigment with Diverse Applications

Protein's 'silent code' influences cell movement

Universal stem cells exhibit the potential for more cost-effective cell therapy

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

New method yields 10 times more accessible details of gene activity in individual cells

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