Cell Death News and Research

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New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

Critical intermediate in normal cellular metabolism may lead to cell death

A recent study shows that a critical intermediate in normal cellular metabolism is also a cause for cell death in the right sense.

27 Apr 2021

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

Researchers have discovered a possible connection between increased vulnerability to COVID-19 infection and exposure to organophosphate pesticides.

27 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

9 Apr 2021

Dopamine-releasing brain cells shed light on Parkinson’s disease

Scientists have found that botulinum toxin—commonly known as Botox—can expose the inner workings of the brain, in addition to smoothing out wrinkles.

From New York University (NYU) 7 Apr 2021

3D-printed system enables the growth of self-organizing brain tissue

A research team has created brain tissue organoids in a tiny 3D-printed system that helps them observe as they grow and develop.

7 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Innovative computational model of cells could help better understand neurodevelopmental disorders

For a long time, researchers have attempted to gain better insights into the development of the cerebral cortex and its layers, since pathologies are associated with this process.

From University of Surrey 1 Apr 2021

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Researchers have uncovered molecular mechanisms involved in removing unwanted cells in the body.

29 Mar 2021

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

A majority of the drugs work through the membranes surrounding the cells of the body.

22 Mar 2021

Key protein regulates cells’ innate defense mechanisms

Scientists from the University of Illinois Chicago (UIC) have found that heparanase (HPSE) is an important regulator of innate defense mechanisms of cells.

17 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Spraying leaves with vitamin C can dramatically increase protein production

The production of high-value pharmaceutical proteins in plants provides benefits over other manufacturing techniques.

10 Mar 2021

New drug target identified for antibiotic-resistant bacteria

Scientists have discovered a key mechanism that enables dangerous bacteria to develop resistance to antibiotics.

9 Mar 2021

Targeted immunotherapy could improve radiotherapy response in cancer cells

Cancers that are resistant to radiotherapy could be rendered susceptible through treatment with immunotherapy, a new study suggests.

9 Mar 2021

Interbacterial toxins may contribute to bacterial genetic diversity

A toxin produced by bacteria as a defense mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

24 Feb 2021

Gut microbiome alterations help melanoma patients to respond to immunotherapy

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.

17 Feb 2021

Antioxidant in green tea may lead to new anti-cancer drugs

Green tea contains an antioxidant that may boost the concentrations of p53, called the “guardian of the genome,” for its potential to kill cancerous cells.

15 Feb 2021