Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists describe pathway that leads to accelerated flowering of plants in low-nitrogen soils

Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.

31 May 2021

Ongoing losses in fish biodiversity continue threatens human diet

A new study of dozens of wild fish species commonly consumed in the Peruvian Amazon says that people there could suffer major nutritional shortages if ongoing losses in fish biodiversity continue. Furthermore, the increasing use of aquaculture and other substitutes may not compensate.

31 May 2021

New microscope helps observe the whole body of the embryo

A research group led by Takashi Saito, of the Ehime University Graduate School of Medicine, developed a 2-photon excitation light-sheet fluorescence microscope which (1) lowers phototoxicity, (2) extends the field of view, and (3) heightens spatial resolution.

31 May 2021

More informed choices of contraceptives can prevent breast cancer

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

31 May 2021

Digital tool predicts protein stability in a cheaper, safer, and faster way

A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability - a vital step in the development of new medicines - is being rolled out by scientists from the UK's University of Bath through their spin-out company, BLOC Labs.

From University of Bath 31 May 2021

New data shows how exercise improves efficiency of energy production in muscle

Mitochondria are the cell's power plants and produce the majority of a cell's energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation.

28 May 2021

Researchers study the mechanical properties of prostate cancer cells treated with anti-cancer drugs

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.

28 May 2021

Non-specific lipid transfer proteins help improve wheat tolerance

Fusarium Head Blight (FHB), often called scab, is a serious disease of small grain cereals like barley and wheat that affects farmers worldwide.

27 May 2021

Study finds unique molecular mechanism by which Hepatitis C virus evades host’s immune system

Hepatitis C virus (HCV) can cause chronic liver infection, which can lead to irreparable liver damage and liver cancer.

From Osaka University 27 May 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Two components of bacterial CRISPR-Cas immunity system are physically linked

Skoltech scientists have demonstrated that the two components of the bacterial CRISPR-Cas immunity system are physically connected.

27 May 2021

Neutralizing antibodies are produced after SARS-CoV-2 infection

A research group from Osaka University led by Professor Hisashi Arase and consisting of researchers from the Research Institute for Microbial Diseases, the Institute for Protein Research, the Immunology Frontier Research Center, the Center for Infectious Diseases, and the Graduate School of Medicine has discovered for the first time that both neutralizing antibodies that protect against infection as well as infection-enhancing antibodies that increase infectivity are produced after infection with SARS-CoV-2 by analyzing antibodies derived from COVID-19 patients.

From Osaka University 26 May 2021

Researchers suggest new strategies for finding drugs that neutralize key enzymes

Scientists from the UK's University of Bath explore racemases - an important type of enzyme that is linked to certain cancers and other life-threatening diseases while also being critical to cell function - in a paper published in the prestigious journal Chemical Society Reviews. The scientists also propose new strategies for finding drugs that neutralize these enzymes.

From University of Bath 26 May 2021

Latest articles provide novel insights into the mechanisms driving pridopidine neuroprotective effects

Prilenia Therapeutics B.V., a clinical stage biotech company focused on developing novel treatments for neurodegenerative and neurodevelopmental disorders, today announces the publication of three peer-reviewed journal articles, highlighting key aspects of the mechanism of action of its lead asset, pridopidine, and the importance of S1R activation as a mechanism to attenuate biological features of neurodegenerative diseases.

25 May 2021

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer therapies for those with these types of cancers, and perhaps further afield.

25 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Plant-based technology reveals key process in virus infection cycle in dynamic detail

A critical process in the infection cycle of viruses has been revealed for the first time in dynamic detail using pioneering plant-based technology.

25 May 2021

Gene expression signatures underlying microglia linked with amyloid plaque phagocytosis

Alzheimer’s disease is the most prevalent form of dementia distinguished by the accumulation of amyloid plaques in the brain.

24 May 2021

Study reveals urine protein biomarkers of bladder cancer

Oncotarget published "Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens" which reported that the current study examines urine samples from 66 subjects, comprising of 31 Urology clinic controls and 35 bladder cancer patients, using a Luminex based screening platform.

24 May 2021

Protein News and Research

Further Reading

Scientists describe pathway that leads to accelerated flowering of plants in low-nitrogen soils

Ongoing losses in fish biodiversity continue threatens human diet

New microscope helps observe the whole body of the embryo

More informed choices of contraceptives can prevent breast cancer

Digital tool predicts protein stability in a cheaper, safer, and faster way

New data shows how exercise improves efficiency of energy production in muscle

Researchers study the mechanical properties of prostate cancer cells treated with anti-cancer drugs

Non-specific lipid transfer proteins help improve wheat tolerance

Study finds unique molecular mechanism by which Hepatitis C virus evades host’s immune system

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Two components of bacterial CRISPR-Cas immunity system are physically linked

Neutralizing antibodies are produced after SARS-CoV-2 infection

Researchers suggest new strategies for finding drugs that neutralize key enzymes

Latest articles provide novel insights into the mechanisms driving pridopidine neuroprotective effects

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

Study could help develop peptide siRNA carrier for human oral cancer

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Plant-based technology reveals key process in virus infection cycle in dynamic detail

Gene expression signatures underlying microglia linked with amyloid plaque phagocytosis

Study reveals urine protein biomarkers of bladder cancer

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