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Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Ophthalmologists and researchers have been looking into mesenchymal stem cells (MSCs) with regenerative and differentiation capacities as a potential therapy option for corneal disorders.

30 May 2022

Research highlights how cornea T cells may track and combat viral infections

According to a new study, the cornea creates a sensitive and restricted immune response to combat infections without causing visual damage.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

CRISPR-CAS9 technique that allows scientists to alter the genetic code of living creatures

Scientists were able to modify the genetic code of living beings ten years ago thanks to a breakthrough technique called CRISPR-CAS9.

27 May 2022

Genetic testing advances help to uncover primary immune deficiency diseases

Infections caused by primary immunodeficiency diseases (PID) can be persistent and life-threatening. More than 450 PIDs have been identified, yet diagnosing them quickly and accurately remains a difficulty.

27 May 2022

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

Researchers develop advanced machine learning to count blood cells

The use of machine learning to do blood cell counts for illness detection rather than costly and often less reliable cell analyzer devices has proven labor-intensive, as the training of the machine learning model requires a tremendous amount of manual annotation activity by humans.

27 May 2022

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

A stomach adult stem cell population can fulfill two distinct functions: either help with digestion under normal conditions or take the lead on injury response. S

26 May 2022

Maternal rhythms help to develop the suprachiasmatic nuclei’s “master clock”

According to a new study published May 24th, 2022, in the open-access journal PLOS Biology by Alena Sumová and coworkers of the Czech Academy of Sciences in Prague, genes within the fetus’s developing clock respond to rhythmic behavior in the mother during fetal development, first before the biological clock starts ticking on its own.

25 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

From The University of Utah 24 May 2022

Cell News and Research

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Research highlights how cornea T cells may track and combat viral infections

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

CRISPR-CAS9 technique that allows scientists to alter the genetic code of living creatures

Genetic testing advances help to uncover primary immune deficiency diseases

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Researchers develop a new biochemical process to analyze plant immunity

Researchers develop advanced machine learning to count blood cells

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

Maternal rhythms help to develop the suprachiasmatic nuclei’s “master clock”

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

Research highlights a novel technique for cancer cells to repair DNA damage

Researchers propose new methods to save the world’s most important crops

Researchers devise a new treatment approach to cure aggressive brain tumors

New study explores how human plastins behave in cells

Research may lead to new therapies for metabolic disorders and other diseases

Researchers understand the mechanisms of deadly fungal infections

Researchers develop primitive endoderm stem cells in mice

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