Metabolites News and Research

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Scientists develop simple, effective fluorescent biosensors widely used in scientific and medical research

Scientists have made it simple for researchers to interpret biological processes all by making a small change to the color palette.

22 Oct 2020

Childhood trauma leads to metabolic changes across generations

People who experienced childhood trauma usually suffer lifelong consequences that impact their physical and mental health.

19 Oct 2020

Innovative machine learning concepts can help develop new drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

15 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Deep learning-based technique could boost drug development

When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.

6 Oct 2020

Analysis of wild tomatoes elucidates genetic basis underlying fruit traits

Domestication and subsequent intensive breeding of tomato had a major impact on fruit ripening and the myriad metabolic processes accompanying it.

29 Sep 2020

Mutant tomato helps to decipher fruiting secrets

It may sound like something out of a science fiction B-movie, but with the help of a mutant tomato, researchers from Japan have discovered that the development process of fruit rewires their central metabolism pathway.

11 Sep 2020

New study reveals metabolic signature of SARS-CoV-2 infection involving signs of multi-organ damage

SARS-CoV-2 can lead to a broad range of symptoms, from absolutely nothing to multi-organ failure, severe respiratory stress, and eventually death.

11 Sep 2020

Researchers to examine plants as potential indicators of human decomposition

Search teams looking for human remains are often slowed by painstaking on-foot pursuits or aerial searches that are obscured by forest cover.

4 Sep 2020

Study: Bacterial cells from different species can combine into unique hybrid cells

Like humans, bacteria live together in communities, sometimes lending a hand -- or in the case of bacteria, a metabolite or two -- to help their neighbors thrive.

3 Sep 2020

Gut bacterium is linked to increased risk of stomach cancer

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable. A new study by researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich explores the role played by this diversity in the early phase of infection in adult humans.

3 Sep 2020

New technique tracks human milk nutrients in infant gut microbiome

A new study in mice helps explain why gut microbiomes of breastfed infants can differ greatly from those of formula-fed infants.

2 Sep 2020

Human gut microbiota may play a significant role in maintaining health

Bacteria and other microorganisms in the digestive tract are linked with dozens of health conditions including high blood pressure, high blood lipids, and body mass index (BMI) according to research presented today at ESC Congress 2020.

28 Aug 2020

Study shows strigolactones enhance tolerance to insects in tobacco plants

A team of researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, has discovered that strigolactones, a class of novel plant hormones, mediate the fine-tuning of the production plant defensive substances in the stem of plants of the wild tobacco species Nicotiana attenuata.

25 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

Researchers identify a new type of PII-like proteins in Lactobacillus hilgardii LMG 7934

The team is led by Associate Professor Ayrat Kayumov (Department of Genetics, Kazan Federal University). In this research, the scientists not only performed genome sequencing, but also found a completely new type of PII-Like Protein PotN.

20 Aug 2020

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures.

19 Aug 2020

Researchers develop new drugs to eradicate parasitic worms

In this breakthrough method, parasitic worms are prevented from using alternative metabolism routes offered by microbes living inside them.

12 Aug 2020

Novel molecule shown to have potential therapeutic effects for arthritis

Arthritis affects almost 2% of the world's population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease. A new molecule developed in the laboratory has been shown to have potential therapeutic effects.

12 Aug 2020

Researchers describe a previously unknown phylum of aquatic Archaea

In a publication in Nature Communications last Friday, NIOZ scientists Nina Dombrowski and Anja Spang and their collaboration partners describe a previously unknown phylum of aquatic Archaea that are likely dependent on partner organisms for growth while potentially being able to conserve some energy by fermentation.

11 Aug 2020