therapeutics News and Research

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The Peptoid Approach to Antiviral Resistance

Antiviral therapies are difficult to develop because viruses can rapidly mutate to become drug resistant.

3 Aug 2023

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023

Alligator Bioscience Announce Milestone Achievement in 2021 Immuno-Oncology Research Collaboration and License Agreement with Orion Corporation

Alligator Bioscience today announced that Technical Feasibility in the second program under the research collaboration and license agreement with Orion Corporation, which aims to discover and develop new bispecific antibody cancer therapeutics, has been achieved.

1 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

T Cells Play a Dual Role in Wasting During Infection

Even though infections can be presented with several different symptoms, one common symptom is known to be the loss of fat and muscle, a process known as wasting.

25 Jul 2023

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.

25 Jul 2023

New Method Creates Embryo-Like Structure That Mimics Gastrulation

Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a "black box" of human development.

21 Jul 2023

Unraveling the Link Between High Body Temperature and Increased Viral Resistance

Researchers from The University of Tokyo unravel the connection between high body temperature and increased viral resistance.

21 Jul 2023

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.

21 Jul 2023

Government Backing UK Engineering Biology Firms to Revolutionise Medicine, Food and Environmental Protection

The UK firms harnessing the power of biology to deliver new medical therapies, means of recycling and environmentally-friendly food sources will be under the spotlight at Downing Street today (Wednesday 19 July) as science leaders and Ministers meet to unleash the full potential of the UK’s engineering biology sector.

19 Jul 2023

New Study Highlights Genetic Variations for a Precision Medicine Approach

There are genetic variations among children with a rare neurodevelopmental disease, according to a new study headed by the Seaver Autism Center for Study and Treatment at Mount Sinai. This discovery could set the path for a precision medicine approach to treating these children.

18 Jul 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

29 Jun 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

Using Pressure to Understand RNA Dynamics

Similar to how there are limitless secrets in space, there is still a lot to discover when looking at biomolecules, which are one trillion times smaller than a meter.

23 Jun 2023

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power.

22 Jun 2023

therapeutics News and Research

The Peptoid Approach to Antiviral Resistance

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Alligator Bioscience Announce Milestone Achievement in 2021 Immuno-Oncology Research Collaboration and License Agreement with Orion Corporation

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

T Cells Play a Dual Role in Wasting During Infection

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

New Method Creates Embryo-Like Structure That Mimics Gastrulation

Unraveling the Link Between High Body Temperature and Increased Viral Resistance

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

Government Backing UK Engineering Biology Firms to Revolutionise Medicine, Food and Environmental Protection

New Study Highlights Genetic Variations for a Precision Medicine Approach

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

The First Programmable RNA-Guided System in Eukaryotes Uncovered

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Using Pressure to Understand RNA Dynamics

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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