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New Research Reveals Infrared Radiation as a Mosquito Host-Seeking Trigger

While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika, and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal.

23 Aug 2024

The Role of DNA Repair Pathways in Antibody Somatic Hypermutation

In a recent online publication in SCIENCE CHINA Life Sciences, researchers from the laboratory of Leng-Siew Yeap at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine published a review article entitled "Molecular Mechanisms of DNA Lesion and Repair During Antibody Somatic Hypermutation". This review comprehensively summarizes the mechanisms involved in the generation of antigen-specific diversified antibodies, with a particular focus on the mechanisms that generate high-frequency point mutations and low-frequency deletions and insertions (indels) in antibody genes.

22 Aug 2024

Mitochondrial DNA Enzymes Prevent Disease Mutations

Researchers at the University of Queensland have identified a mechanism in DNA that controls the inheritance of disease-causing mutations.

22 Aug 2024

Enzyme Therapy Shows Promise for Parkinson's Disease

A preclinical investigation conducted by Weill Cornell Medicine researchers has shown an unexpectedly important role for an enzyme called PGK1 in the synthesis of chemical energy in brain cells.

22 Aug 2024

Two Genes Control Explosive Taste Bud Growth in Cavefish

Over thousands of years, cavefish evolved and lost their vision, earning the moniker "the blind cavefish," but some cavefish also developed an inordinate number of taste buds on the head and chin.

16 Aug 2024

diaago Launches Innovative Invensify Insuridge Shipper: A New Era in Sample Transportation

diaago, a leading distributor in the scientific community, is thrilled to announce the launch of the Invensify Insuridge Shipper, a revolutionary product designed to elevate the standards of biological sample transportation.

From diaago 9 Aug 2024

Research Unlocks Secrets of Stem Cell Retention in Bone Marrow

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells. The findings, made in mice, were published today in the journal Science.

9 Aug 2024

New Findings Shed Light on ATM Activation in DNA Repair

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

9 Aug 2024

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

The ability to alter or prevent the expression of faulty genes in the brain could be leveraged as a powerful therapeutic against neurodegenerative disease. However, the molecular underpinnings of the living brain are still largely inaccessible, hampering progress on such promising therapeutics.

9 Aug 2024

Advancements in Grape Genomics Promise Enhanced Breeding Strategies

Grapes are economically and culturally significant worldwide, but climate change has posed substantial challenges to grape production in recent decades.

8 Aug 2024

Detailed Analysis of Cucumber Centromeres Uncovers Key DNA Sequences and Retrotransposons

Centromeres are crucial for chromosome segregation during cell division and consist of repetitive DNA sequences.

8 Aug 2024

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

6 Aug 2024

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

5 Aug 2024

Multispecies Transmission of Avian Flu Virus Includes Dairy Cattle, Cats, and Raccoons

A viral spillover of the highly pathogenic avian influenza virus belonging to the hemagglutinin 5 neuraminidase 1 (H5N1) 2.3.4.4b clade among herds of dairy cattle.

5 Aug 2024

Breakthrough in Understanding Brain's Master Protein

Proteins engage in intricate molecular movements to fulfill their biological roles. The NMDAR protein, crucial for brain function, performs a particularly complex dance.

1 Aug 2024

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

The rapid detection of Mycobacterium tuberculosis, the etiological agent of tuberculosis.

1 Aug 2024

Gut Microbiome Influences Cancer Risk Through Carcinogen Metabolism

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world.

1 Aug 2024

Study Reveals Strigolactones as Key Regulators of Tomato Flowering

In an article published in the journal PNAS, researchers at the University of São Paulo's Luiz de Queiroz College of Agriculture (ESALQ-USP) in Brazil describe for the first time how strigolactones, plant hormones discovered several decades ago, control flowering and fruiting in the tomato (Solanum lycopersicum). The findings of their study point to a new opportunity for management of fruiting time and could have a significant impact on total yields for this crop.

1 Aug 2024

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

The liver can renew itself quite well. Maintaining organ function and recuperating from surgery or injury depends on this quality. Using clinical samples, researchers from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden, and ETH Zurich have examined the changes in liver cell types before and following regeneration.

31 Jul 2024

Rapid Parkinson's Model Opens Door to Personalized Treatments

Scientists at Brigham and Women’s Hospital, a key member of the Mass General Brigham healthcare system, have created a model that swiftly transforms stem cells into brain cells exhibiting protein structures associated with Parkinson’s disease (PD).

30 Jul 2024

Laboratory News and Research

New Research Reveals Infrared Radiation as a Mosquito Host-Seeking Trigger

The Role of DNA Repair Pathways in Antibody Somatic Hypermutation

Mitochondrial DNA Enzymes Prevent Disease Mutations

Enzyme Therapy Shows Promise for Parkinson's Disease

Two Genes Control Explosive Taste Bud Growth in Cavefish

diaago Launches Innovative Invensify Insuridge Shipper: A New Era in Sample Transportation

Research Unlocks Secrets of Stem Cell Retention in Bone Marrow

New Findings Shed Light on ATM Activation in DNA Repair

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

Advancements in Grape Genomics Promise Enhanced Breeding Strategies

Detailed Analysis of Cucumber Centromeres Uncovers Key DNA Sequences and Retrotransposons

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Multispecies Transmission of Avian Flu Virus Includes Dairy Cattle, Cats, and Raccoons

Breakthrough in Understanding Brain's Master Protein

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

Gut Microbiome Influences Cancer Risk Through Carcinogen Metabolism

Study Reveals Strigolactones as Key Regulators of Tomato Flowering

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

Rapid Parkinson's Model Opens Door to Personalized Treatments

Lab Automation - Third Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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