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Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

11 Apr 2023

A New, Cost-Effective Therapy to Treat a Wide Range of Cancers

A potential immunotherapy method for treating metastatic melanoma is adoptive cell therapy (ACT). The method, which utilizes the use of immune cells extracted from the patient’s own tumors, could offer cancer patients new options for treatment by eschewing radiation therapies and harsh chemotherapy drugs.

11 Apr 2023

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.

11 Apr 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

CRISPR-Cas9 Driven Gene-Editing Tool Models Liver Cancer Tumor Subtypes

Mutations in human genes can cause serious issues, such as colon or liver cancer. However, cancer is a very complex condition. Mutations in the same genes can result in distinct kinds of cancers in different persons.

11 Apr 2023

Unraveling Regulatory Mechanisms When Plants Use Nitrogenous Fertilizers in the Roots

Insights into gene and protein control systems that regulate the use of nitrogen by plant roots could help develop crops that require less nitrogenous fertilizers to produce acceptable yields.

11 Apr 2023

New Research Calls for a Reappraisal of Plant Domestication Process

The story of how ancient wolves came to claim a place near the campfire as humanity's best friend is a familiar tale (even if scientists are still working out some of the specifics).

11 Apr 2023

Integrated-Gut-Liver-on-a-Chip can Improve Understanding of Non-Alcoholic Fatty Liver Disease

A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs.

10 Apr 2023

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ways to treat AML, while preserving normal blood development.

10 Apr 2023

The Modified Development Potential of Worm Embryonic Cells

A startling discovery that challenges the conventional wisdom that the majority of the hereditary information for cell differentiation is encoded within DNA and other genetic factors has been made regarding how specific proteins within the chromosomes of roundworms facilitate their offspring to develop specialized cells generations later.

10 Apr 2023

Key Mediator of Anhedonia-Like Behavior Identified

Researchers uncovered a stress-regulated gene that is important in the relationship between chronic stress and typical depressed behavior in mice.

10 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Trinity Scientists Discover New Mechanisms Involved in Establishing Cellular Identity

A team of scientists led by those in Trinity College Dublin has discovered new mechanisms involved in establishing cellular identity, a process that ensures the billions of different cells in our bodies do the correct job.

10 Apr 2023

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

10 Apr 2023

Researchers Identify Antibody that may Block Infection by All Dominant SARS-CoV-2 Variants

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.

10 Apr 2023

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs.

7 Apr 2023

Strawberry Inflorescence Research Provides Tools for Genomics-Based Plant Breeding

Researchers from the University of Helsinki, in collaboration with their Canadian colleagues, have demonstrated how strawberry inflorescence development is dictated by the small growing points, called meristems.

7 Apr 2023

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress.

7 Apr 2023

Wastewater Surveillance may Help Monitor the Spread of Candida Auris, Study Shows

A rapid spike in cases of a potentially deadly, drug-resistant fungus has concerned public health officials across the nation.

7 Apr 2023

Novel Tridimensional Anticancer Agents Have the Ability to Overcome Drug Resistance in Cancer Cells

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

Research News and Research

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

A New, Cost-Effective Therapy to Treat a Wide Range of Cancers

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 Driven Gene-Editing Tool Models Liver Cancer Tumor Subtypes

Unraveling Regulatory Mechanisms When Plants Use Nitrogenous Fertilizers in the Roots

New Research Calls for a Reappraisal of Plant Domestication Process

Integrated-Gut-Liver-on-a-Chip can Improve Understanding of Non-Alcoholic Fatty Liver Disease

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

The Modified Development Potential of Worm Embryonic Cells

Key Mediator of Anhedonia-Like Behavior Identified

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Trinity Scientists Discover New Mechanisms Involved in Establishing Cellular Identity

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

Researchers Identify Antibody that may Block Infection by All Dominant SARS-CoV-2 Variants

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Strawberry Inflorescence Research Provides Tools for Genomics-Based Plant Breeding

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

Wastewater Surveillance may Help Monitor the Spread of Candida Auris, Study Shows

Novel Tridimensional Anticancer Agents Have the Ability to Overcome Drug Resistance in Cancer Cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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