Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Soil microbes are critical players in corn heterosis

The tiny organisms living in soil may have a greater effect on the yield and pest and disease resistance of crop plants grown in that soil than previously known.

22 Jul 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Isoflavone diet plus metabolizing gut bacteria may provide protection against MS

A new University of Iowa study suggests that metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis (MS), may provide protection against the disease.

14 Jul 2021

Mass spectrometry: Important analytical tool to understand Huntington’s disease proteome

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

Specific chemical feature of a key protein may lead to neurodegenerative diseases

Scientists have found that a particular chemical feature of a crucial protein may cause it to build up in the brain and lead to various disorders.

28 Jun 2021

A new treatment approach against SARS-CoV-2

Scientists have come up with a new method to treat SARS-CoV-2 infection by fixing the cell damage instead of fighting the virus directly.

21 Jun 2021

Study decodes the activation mechanism of immune cells

Chemokines are small proteins that adhere to these chemokine receptors and regulate the behavior and movement of white blood cells.

17 Jun 2021

Misfolded tau proteins cause progressive degeneration in Alzheimer's disease

According to a study performed by researchers from the Van Andel Institute and the University of Pennsylvania, misfolded proteins that impair neurons in Alzheimer’s disease travel the “roads” of the brain, similar to a supply truck crossing the countryside.

11 Jun 2021

New study on genotype-phenotype associations sheds light on human complex traits, diseases

A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.

2 Jun 2021

Simple electromechanical device can be used for deep tissue pathology diagnosis

By putting a piece of soft, strain-sensing sheet on the skin may be able to detect skin disorders non-invasively and in real-time very soon.

31 May 2021

Novel drug is highly effective in preventing severe COVID-19 in mice

The drug diABZI -- which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2,

31 May 2021

Scientists identify mechanism by which head and neck cancer cells subvert adjacent normal tissue

Up to half of patients with head and neck squamous cell carcinoma will experience tumor recurrence or new tumors--tumors that often spread and are difficult to treat.

28 May 2021

Immune system’s killer T cells make mistakes in distinguishing healthy from infectious cell

When it comes to differentiating between a healthy cell and an infectious cell that has to be killed, the immune system’s killer T cells might make mistakes.

27 May 2021

New method helps tests large groups for SARS-CoV-2 infection

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Convergence science are needed to prevent plant disease outbreaks

Plant diseases don't stop at national borders and miles of oceans don't prevent their spread, either. That's why plant disease surveillance, improved detection systems, and global predictive disease modeling are necessary to mitigate future disease outbreaks and protect the global food supply, according to a team of researchers in a new commentary published in Proceedings of the National Academy of Sciences.

24 May 2021

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells produce antibodies in response to a pathogen or a vaccine, providing immunity.

14 May 2021

Scientists discover genes responsible for smoking-related decline in lung function

(Boston)--Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing.

12 May 2021