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Study shows how specific gene mutations cause different types of diseases

Renowned cancer experts have resolved a query of how different types of mutations in a single gene are responsible for causing various types of diseases.

15 Jan 2021

Researchers make new discovery in the quest for novel antibiotics

Scientists who highlighted the bug-busting properties of bacteria in Northern Irish soil have made another exciting discovery in the quest to discover new antibiotics.

15 Jan 2021

Researchers use heat map data to reverse engineer chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Speciation process takes place in the presence of maximal gene flow, indicates study

Spatial isolation is known to promote speciation - but researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have now shown that, at least in yeast, the opposite is also true. New ecological variants can also evolve within thoroughly mixed populations.

15 Jan 2021

New barcoding system improves portable DNA sequencing to monitor pathogens more effectively

Scientists have discovered an easy way to remove nearly all sequencing errors created by a commonly used portable DNA sequencer.

13 Jan 2021

Circadian rhythms control killer cells in the immune system

According to an analysis of data humans’ ability to combat diseases may largely depend on day-to-day circadian cycles than previously believed.

13 Jan 2021

Researchers develop novel nanobodies against SARS coronavirus-2

An international research team led by the University of Bonn has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Researchers determine atomic structure of coronavirus protein linked to disease severity

A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells.

13 Jan 2021

Researchers show how the genetic material travels from cell to cell

The genetic material of plants, animals, and humans is well protected in the nucleus of each cell and stores all the information that forms an organism. For example, information about the size or color of flowers, hair or fur is predefined here.

12 Jan 2021

Study unravels the mystery of infectious virion formation

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus 'package up' their genetic code, allowing them to infect cells.

11 Jan 2021

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.

8 Jan 2021

Scientists use stem cells to reverse memory and learning deficits in mice with craniosynostosis

In an effort to regenerate portions of the skull, researchers have successfully used stem cells, corrected the shape of the skull, and thus reversed learning and memory deficits in young mice afflicted with craniosynostosis.

8 Jan 2021

Study uncovers unusual sex chromosomes of Australian iconic animals

The sex chromosomes genetically define the developmental fate of an embryo to become a male or a female individual, and usually, appear as one pair of morphologically different chromosomes between sexes.

8 Jan 2021

New deep neural network predicts transcription factors from protein sequences

A collaborative team of researchers have developed a deep neural network called DeepTFactor that predicts transcription factors from protein sequences.

8 Jan 2021

Scientists identify gene that helps rice adapt to low soil nitrogen

Chinese researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) have identified a gene that plays a significant role in helping rice adjust to low nitrogen levels in soil.

7 Jan 2021

Study may lead to new treatments for autoimmune diseases

According to a research team, headed by Decio L. Eizirik, MD, PhD, a Scientific Director from the Indiana Biosciences Research Institute Diabetes Center, new treatments for autoimmune disorders can be identified by studying both target tissues and the immune system together.

7 Jan 2021

Researchers map platypus genome to understand its bizarre characteristics

Often considered the world's oddest mammal, Australia's beaver-like, duck-billed platypus exhibits an array of bizarre characteristics: it lays eggs instead of giving birth to live babies, sweats milk, has venomous spurs and is even equipped with 10 sex chromosomes.

7 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

DNA-editing technique used to extend lifespan of mice with progeria

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.

From National Human Genome Research Institute (NHGRI) 7 Jan 2021

Microbe found in the colon may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

7 Jan 2021