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Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Antibodies from natural controllers appear to play crucial role in eliminating hepatitis B virus

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

From Institut Pasteur 14 Aug 2020

Researchers identify metabolically responsive “switch” that reduces tumor growth

According to a study the enzyme called serine palmitoyl-transferase can be utilized as a metabolically responsive “switch” that reduces the growth of tumor.

13 Aug 2020

Researchers use 3D printing to produce cardiomyocytes from stem cells

The life of each human being starts from a single cell, which subsequently divides to ultimately form into an embryo.

12 Aug 2020

Oxytocin can help control and prevent osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

11 Aug 2020

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

AZoLifeSciences talks to Dr. Shane Liddelow about their research into discovering the critical role of astrocytes in neurodegenerative diseases like glaucoma.

From New York University (NYU) 29 Jul 2020

Novel label-free imaging method can differentiate between quiescent and activated T cells

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

28 Jul 2020

Optical fibers made of agar have potential for various medical applications

An optical fiber made of agar has been produced at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil. This device is edible, biocompatible and biodegradable.

27 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Researchers identify a potential biomarker of aging

The skin is the only organ that shows age more profoundly. While researchers have hypothesized about the ravages of time on skin and also the epidermal stem cells that undergo differentiation to restore the external layer of the skin, no suitable method is available to assess their aging at the molecular level.

22 Jul 2020

Scientist receives DoD grant to develop freeze-dried synthetic platelets

A Case Western Reserve University scientist, who has for more than a decade pioneered research into synthetic platelet substitutes, has been awarded a $3.8 million grant by the U.S. Department of Defense (DOD) to develop freeze-dried artificial platelets that can treat bleeding in wounded soldiers in the battlefield before they can be taken to a hospital.

22 Jul 2020

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

21 Jul 2020

in vivo News and Research

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

New bioluminescent reporter tracks DNA double stranded break repair in cells

Antibodies from natural controllers appear to play crucial role in eliminating hepatitis B virus

Researchers identify metabolically responsive “switch” that reduces tumor growth

Researchers use 3D printing to produce cardiomyocytes from stem cells

Oxytocin can help control and prevent osteoporosis

New method targets hidden HIV viral reservoirs during antiretroviral therapy

A new cell-based gene therapy approach to correct hemophilia A

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

Novel label-free imaging method can differentiate between quiescent and activated T cells

Optical fibers made of agar have potential for various medical applications

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

Researchers identify a potential biomarker of aging

Scientist receives DoD grant to develop freeze-dried synthetic platelets

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

Study reveals anti-viral properties of curcumin

SARS-CoV-2 protein effectively shuts down host protein production, shows study

Modified mRNAs improve efficiency of protein synthesis

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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