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TMEM106B gene reveals the causes of neurodegenerative diseases

Across the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal lobar degeneration (FTLD), which develop when neurons in specific parts of the brain stop functioning - triggering memory loss and other behavioral or personality changes.

10 Jul 2020

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems of Biology, RAS. The findings are reported in PLOS One.

10 Jul 2020

Brain's dedicated immune cells clear paths through 'scaffolding' to let neurons talk

To make new memories, our brain cells first must find one another. Small protrusions that bud out from the ends of neurons' long, branching tentacles dock neurons together so they can talk.

7 Jul 2020

Study reveals the role of alpha-synuclein in Parkinson’s disease

In people affected by Parkinson’s, clusters of alpha-synuclein or α-synuclein, also referred to as the “Parkinson’s protein,” are detected in the brain.

6 Jul 2020

Researchers identify osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Astrocytes may play a key role in neurodegenerative disorders

According to a new research performed in rodents, cells that usually nurture nerves may actually destroy them following a brain injury.

From New York University (NYU) 24 Jun 2020

Fish Oil May Help With Depression

A study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

17 Jun 2020

Researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

11 Jun 2020

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington's disease in a new study published today in eLife.

10 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020

A remote optical stimulation for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

2 Jun 2020

Research identifies how neuronal transmission is disrupted in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

29 May 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

New model mimics early embryonic stages of the human brain

We know a lot about the human brain, but very little about how it is formed. In particular, the stages from the second to the seventh week of embryonic development have so far been virtually unknown territory to brain researchers.

26 May 2020

Using light to control the viability and mobility of individual cells

Photopharmacology is the study that examines the use of light to change the impact of drugs on and off. For the first time, researchers from Jena, Munich, and New York have successfully applied this technique to regulate a component of cells that was earlier believed to be inaccessible.

18 May 2020