Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Research links blood-clotting protein with CNS B-cell lymphoma growth

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

18 Feb 2021

Gene-based blood test may predict treatment success in people with metastatic melanoma

A test that monitors blood levels of DNA fragments released by dying tumor cells may serve as an accurate early indicator of treatment success in people in late stages of one of the most aggressive forms of skin cancer, a new study finds.

From New York University (NYU) 15 Feb 2021

Rebuilding soil microbiomes becomes challenging in high- tunnel soils with salt and nitrogen

The presence of high salt and nitrogen concentrations in high- tunnel soils may make it more challenging to rebuild a healthy soil microbiome following a soil-clearing event, according to microbial ecologists in Penn State's College of Agricultural Sciences.

From Penn State University 12 Feb 2021

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

11 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

From Penn State University 10 Feb 2021

New insights into the biology of chytrid fungus responsible for deadly skin infection

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

9 Feb 2021

Scientists implicate disruption in prenatal neurogenesis in the development of autism

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

9 Feb 2021

Targeting glycoprotein could improve response to immune checkpoint therapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

29 Jan 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

New study sheds light on citrus greening disease

Huanglongbing (HLB), also called citrus greening disease, is detrimental to the citrus industry and causes unparalleled levels of destruction around the world. But despite this fact, there is no proven treatment for this.

22 Jan 2021

Cancer cells can exchange and recombine their genetic material, shows study

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes.

22 Jan 2021

Fecal microbiome differs in healthy and food-allergic twins

A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition. The results were published on Jan. 19 in the Journal of Clinical Investigation.

20 Jan 2021

Metabolites may be predictive indicators for recurrent major depressive disorder

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.

13 Jan 2021

New model can help identify potential drug targets for ulcerative colitis

Scientists from the Lerner Research Institute at Cleveland Clinic have designed an innovative, patient-derived model of ulcerative colitis that will help scale up studies into new therapies for chronic inflammatory bowel disease.

12 Jan 2021

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.

8 Jan 2021

Study identifies the effects of nutritional deficiency on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

4 Jan 2021

Pathology News and Research

Research links blood-clotting protein with CNS B-cell lymphoma growth

Gene-based blood test may predict treatment success in people with metastatic melanoma

Rebuilding soil microbiomes becomes challenging in high- tunnel soils with salt and nitrogen

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Unusual DNA folding leads to higher mutation rates

New insights into the biology of chytrid fungus responsible for deadly skin infection

Scientists implicate disruption in prenatal neurogenesis in the development of autism

Targeting glycoprotein could improve response to immune checkpoint therapy

Unique proteomics-based technology can help diagnose breast cancer more accurately

New study sheds light on citrus greening disease

Cancer cells can exchange and recombine their genetic material, shows study

Fecal microbiome differs in healthy and food-allergic twins

Metabolites may be predictive indicators for recurrent major depressive disorder

New model can help identify potential drug targets for ulcerative colitis

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Study identifies the effects of nutritional deficiency on patient survival after cardiac surgery

Researchers demonstrate potential preventive treatment for Crohn's disease

ECSIT protein can shed light on the origin of Alzheimer's disease

Researchers detect new immune cells that act as major driver of breast cancer growth

Study: Fungi have proteins that allow them to sense consumable things

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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