in vitro News and Research

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Cell membranes can boost the production of protein-based vaccines

Synthetic biologists have cracked open a cellular membrane, identifying a new method to boost the production yields of protein-based vaccines by five times.

26 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Study finds an amyloid link between melanoma and Parkinson’s disease

Parkinson’s disease is a neurodegenerative disorder and melanoma is a type of skin cancer but on the surface, these disorders do not seem to have much in common.

8 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

New high-throughput system for testing drug candidates to treat neurodegenerative diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

19 Mar 2021

Alzheimer’s proteins linked to age-related vision loss

A recently published study has demonstrated a close correlation between proteins linked to age-related vision loss and Alzheimer’s disease.

11 Mar 2021

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

5 Mar 2021

Scientists gain new insights into ribosome formation to identify potential drug targets

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Reportedly, Curcumin has several physiological activities, which include anti-inflammatory, anti-oxidation, anti-amyloid, and anti-cancer properties.

1 Mar 2021

New platform could help treat neurodegenerative diseases using regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

Fungal hybridization confers greater adaptive potential in Verticillium longisporum

Several plant pathogens belong to the genus Verticillium and affect many different plant hosts.

24 Feb 2021

Testing for inherited genes can help understand future cancer risk in pediatric patients

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

17 Feb 2021

Bernese researchers create sophisticated lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

10 Feb 2021

Study reveals molecular details of how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process.

9 Feb 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

New approach to biomaterial production may ease environmental burden of forestry, agriculture

It takes a lot to make a wooden table. Grow a tree, cut it down, transport it, mill it ... you get the point. It's a decades-long process. Luis Fernando Velásquez-García suggests a simpler solution: "If you want a table, then you should just grow a table."

22 Jan 2021