Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

New Research Into the Impact of Microplastics and Nanoplastics on Human Health is Urgently Required Due to ‘Significant Threat’ to Human Health

A new metastudy published in Cambridge Prisms: Plastics by Cambridge University Press, has identified a body of evidence demonstrating the negative impact of microplastics and nanoplastics (MPs and NPs) on human health and identifying the limitations of current research.

20 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

Chemists Develop Two-Step Method to Create Promising Molecules for Life Sciences Research

Organic compounds in the field of chemistry range from simple hydrocarbons to complex molecules, with diverse functional groups added to the main carbon backbone.

30 Jan 2024

New Horizons in Chemical Biology: A Novel Approach to Synthesize Dibenzothiophene S-Oxides

Dibenzothiophene S-oxides are important in various biochemical processes. However, their synthesis using conventional methods is not easy.

30 Jan 2024

Unlocking the Gut's Metabolic Secrets

The variety of enzymes that microbes employ to make energy in the low-oxygen environment of the gut is highlighted by a survey of bacterial genomes.

8 Jan 2024

“Sugar” Molecule in Cells Plays Crucial Role in Disease Prevention

The body’s inherent production of a sugar-based molecule plays a crucial role in various cellular functions, including growth, differentiation into different cell types, self-destruction if necessary, and more.

29 Nov 2023

Understanding Mitochondrial Adaptations to Cellular Metabolism

Employing advanced super-resolution microscopes, scientists from the University of California, Irvine, and the University of Pennsylvania have, for the inaugural time, witnessed the processes of electrical charge and discharge within mitochondria extracted from cells.

28 Nov 2023

Study Uncovers Novel Genes Linked to Coronary Artery Calcification

An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States.

12 Oct 2023

Schizophrenia-Linked Chromosome Deletion Affects Mitochondria

Investigators are learning more about how schizophrenia develops by investigating the most powerful known genetic risk factor.

22 Aug 2023

5-ALA Opens New Avenues for Treating Mitochondrial Disorders

At the Tokyo Metropolitan University, researchers have shown that 5-aminolevulinic acid (5-ALA) aids bypass deficiencies in Complex I (CI), the first in a series of protein complexes that transport electrons and assist in powering the mitochondria.

17 Jul 2023

Can Temperature Influence the Octopus Neural Transcriptome?

Each cell has a finite set of instructions inscribed in its DNA. Life, on the other hand, is unpredictable, and when the situation changes, animals must change.

9 Jun 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Experts Unravel the Crystal Structure of CENP-E

Anticancer drugs are essential in cancer treatment, but their toxicity is not always restricted to cancer cells, resulting in serious side effects.

5 Apr 2023

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Regular exercise can guarantee quality of life and longevity, specialists agree. However, exactly how exercise influences the functioning of muscle cells is poorly understood.

30 Mar 2023

Artificial cells to serve as the powerhouse of the future

Chloroplasts and mitochondria are responsible for producing energy in nature, which is essential for creating sustainable, artificial cells in the lab. In addition to being “the powerhouses of the cell,” as the adage from middle school biology goes, mitochondria are also one of the most difficult intracellular components to artificially clone.

30 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Describing the molecular basis behind the ultrafast contraction of Spirostomum

Antonie van Leeuwenhoek stated that a single-celled eukaryote (Vorticella) and its appealing ultrafast cell contraction was the first set of discoveries. This was told in his famous letter to the Royal Society dated October 9th, 1676.

23 Feb 2023

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

17 Feb 2023

New method to treat MRSA infections with penicillin-type drugs

Researchers from the University of Galway have reported a new discovery that could enhance treatment options for superbug MRSA infections using penicillin-type antibiotics that have proven ineffective on their own.

18 Jan 2023