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Experts explain left–right asymmetry development in the embryo

Research on the development of symmetry in mice embryos is anticipated to provide a deeper understanding of the causes of disease.

21 Oct 2021

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Alternative splicing can lead to the formation of numerous protein variants. For the first time, alternative splicing has now been systematically analysed for the family of glutamate receptors.

17 Jun 2021

New gene therapy could help treat Duchenne muscular dystrophy

Researchers from UT Southwestern used a new kind of gene therapy to successfully treat mice with Duchenne muscular dystrophy (DMD), distinctively employing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein missing in several DMD patients.

3 May 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

Jumping genes are an important force in the creation of new genes during evolution, shows study

In the same way that Lego pieces can be arranged in new ways to build a variety of structures, genetic elements can be mixed and matched to create new genes, according to new research.

23 Feb 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems of Biology, RAS. The findings are reported in PLOS One.

10 Jul 2020

Study develops a memory-intensive approach to visualize genomes

At Ulm University in Germany, a new method has been devised for developing pan-genome subgraphs at various granularities without the need to wait several hours or days for the software to process the complete genome.

27 Apr 2020