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Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

Harnessing Proteomics to Explore the Role of Probiotic Bacteria in Human Health

The currently available proteomics strategies can be used to identify and quantify probiotic bacterial proteins.

19 Aug 2024

Insights into Host Defense Mechanisms Through Cell Death and Immune Pathways

A new review was published as the cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15, entitled, "Types of cell death and their relations to host immunological pathways".

19 Aug 2024

The Importance of Antioxidant Therapy in Preventing Parkinson's Disease

The neurodegenerative condition known as Parkinson's disease is caused by the death of neurons that generate dopamine, a neurotransmitter essential for both motor control and cognitive function.

6 Aug 2024

Mast Cells Recruit Neutrophils in Immune Response

Mast cells are well-known for their part in allergic reactions, but the immune system relies heavily on them. They release chemicals in response to allergens, which cause common allergy symptoms like tissue swelling and inflammation.

5 Aug 2024

Antisense Therapy Shows Promise Against Parkinson's

Parkinson's disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called α-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies and Lewy neurites depending on their subcellular localization, can spread by continuously causing normal endogenous aSyn to misfold.

26 Jul 2024

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

24 Jul 2024

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

12 Jun 2024

Novel Lipopeptide from Serratia marcescens Shows Promise Against Staphylococcus aureus Infections

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

7 Jun 2024

UC San Diego Researchers Find Cause of Cellular 'Short-Circuit'

A group of researchers at University of California San Diego has identified the cause of a "short-circuit" in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases.

5 Jun 2024

Mitochondrial Phosphate Carrier MIR1: A Key Player in Candida albicans Virulence

This study is led by Professor Yan Wang (School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai, China). Her team found that the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans.

23 May 2024

Exploring Cell-in-Cell Events Across the Tree of Life

In a new review paper, Carlo Maley and Arizona State University colleagues describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another.

22 May 2024

Unveiling the Anti-Inflammatory and Anti-Obesity Potential of Menthol-Derived Esters

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues

20 May 2024

Unveiling the Role of NCLX Protein in Mitochondrial Calcium Regulation and Autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction.

3 May 2024

Intracellular News and Research

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Harnessing Proteomics to Explore the Role of Probiotic Bacteria in Human Health

Insights into Host Defense Mechanisms Through Cell Death and Immune Pathways

The Importance of Antioxidant Therapy in Preventing Parkinson's Disease

Mast Cells Recruit Neutrophils in Immune Response

Antisense Therapy Shows Promise Against Parkinson's

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Novel Lipopeptide from Serratia marcescens Shows Promise Against Staphylococcus aureus Infections

UC San Diego Researchers Find Cause of Cellular 'Short-Circuit'

Mitochondrial Phosphate Carrier MIR1: A Key Player in Candida albicans Virulence

Exploring Cell-in-Cell Events Across the Tree of Life

Unveiling the Anti-Inflammatory and Anti-Obesity Potential of Menthol-Derived Esters

Unveiling the Role of NCLX Protein in Mitochondrial Calcium Regulation and Autophagy

Unlocking the Secrets of Lipid Droplet Proteins in Arabidopsis Thaliana Leaves

New Delivery System Opens the Door to Gene-Silencing Therapy

Rare YKT6 Gene Variants Linked to New Neurological Disorder

Scientists Pioneer mRNA Approach to Target Alzheimer's Protein

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Scientists Pinpoint Gene Linked to Neuronal Susceptibility in Alzheimer’s Disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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