Lung Disease News and Research

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Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Newly developed premature cells can support early heart development

A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.

23 Aug 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Inhibition of necroptosis may be a new therapeutic approach to treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease (COPD), an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

21 Jun 2021

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

5 May 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Gut mycobiome correlates with metabolic outcomes in response to diet

Studies of the microbiome in the human gut focus mainly on bacteria. Other microbes that are also present in the gut -- viruses, protists, archaea and fungi -- have been largely overlooked.

8 Mar 2021

Bernese researchers create sophisticated lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

10 Feb 2021

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

23 Dec 2020

Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

TGen identifies genetic target that could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Researchers identify new therapeutic target to fight COVID-19 disease

In COVID-19 patients with severe lung disease, targeting the endothelial cells—that is, cells comprising the blood vessel wall, which control oxygen exchange between the bloodstream and airways—may be an innovative strategy to restore normal function of the lungs.

15 Dec 2020

Study links air pollution and diabetes to interstitial lung disease

People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate.

10 Dec 2020

Scientists identify a genetic basis for ANCA-associated vasculitis

Autoimmune disease is fundamentally a mystery: whyever should an organism systematically set out to harm itself? Now, researchers at the University of Tsukuba have identified a genetic basis for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, an autoimmune systemic disease that damages organs by targeting small blood vessels in a genetic association study.

5 Nov 2020

Lung Disease News and Research

Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

Newly developed premature cells can support early heart development

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Universal stem cells exhibit the potential for more cost-effective cell therapy

Inhibition of necroptosis may be a new therapeutic approach to treating COPD

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Gut mycobiome correlates with metabolic outcomes in response to diet

Bernese researchers create sophisticated lung-on-chip

Scientists discover molecular defects associated with rare genetic disorder in children

Researchers discover protein that may trigger lung scarring

TGen identifies genetic target that could help explain the variation in COVID-19 effects

Researchers identify new therapeutic target to fight COVID-19 disease

Study links air pollution and diabetes to interstitial lung disease

Scientists identify a genetic basis for ANCA-associated vasculitis

Ketogenic diets can prevent or reverse heart failure caused by metabolic process

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Researchers identify protein that causes adverse side effects in gastric cancer patients

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