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Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases.

11 Nov 2021

Study sheds light on how genes and air pollution elevate healthy people’s depression risk

A genetic predisposition for depression combined with exposure to high-particulate-matter air pollution greatly elevates the risk that healthy people will experience depression, according to a first-of-its-kind study published today in the Proceedings of the National Academies of Sciences from neuroscientists at the Lieber Institute for Brain Development, on the Johns Hopkins Medical Campus, and Peking University in Beijing, China.

9 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Technion researchers explore the brain's potential to cause diseases on its own

Your phone pings. It's a notification from your friend, who you just went out for a drink with last night. According to her text, she has just tested positive for COVID-19.

9 Nov 2021

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

8 Nov 2021

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

8 Nov 2021

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University of California, Davis.

From The University of California, Davis 2 Nov 2021

Study reveals what causes T cells to be non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

1 Nov 2021

Study unravels unknown facts about SARS-CoV-2 infection

Around 3%–10% of the individuals infected by the SARS-CoV-2 experience moderate to severe disease.

1 Nov 2021

Genetic markers linked to increased lipopolysaccharide level in blood discovered

Lipopolysaccharide (LPS), a bacterial component, is a toxin and its increased concentrations in the blood induce sepsis.

29 Oct 2021

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response.

27 Oct 2021

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

Inflammation News and Research

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Study sheds light on how genes and air pollution elevate healthy people’s depression risk

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Technion researchers explore the brain's potential to cause diseases on its own

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Study reveals what causes T cells to be non-responsive to immunotherapy

Study unravels unknown facts about SARS-CoV-2 infection

Genetic markers linked to increased lipopolysaccharide level in blood discovered

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Mice study shows how air pollution reduces sperm count by causing brain inflammation

Specific amino acids act against neurodegenerative processes, says study

New insights into the role of fat cells in cognitive decline and neurodegeneration

Enteric glial cells play a major role in gut immunity, says new study

Viral diseases likely to contribute to neurodegeneration, says study

Scientists reveal the importance of circadian rhythm on the immune system

Scientists show how skin T cells can damage other organs in stem cell transplant patients

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

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