Immune System News and Research

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Importance of epigenetic regulation in the recovery of T cells

In stem cell transplants for leukemia treatment, the patient’s hematopoietic system is removed and replaced with hematopoietic cells from donors.

10 Feb 2023

Novel compound curtails influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

10 Feb 2023

Combination of two types of immune cells helps predict response to cancer immunotherapy

Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy.

10 Feb 2023

Telomeres, mitochondria, and inflammation: Working in synergy to fight cancer

The telomeres, or ends of the chromosomes, increasingly shorten as people age. Recently, Salk researchers found that when telomeres are very short, they can still interact with the mitochondria, the cell’s powerhouses.

9 Feb 2023

Protein that facilitates cancer-causing viruses dodge the immune system

Numerous cancers have been related to the viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV). For the first time, UNC School of Medicine researchers have shown that these viruses elude the innate immune response by using a human protein called barrier-to-autointegration factor 1, or BAF, which enables the viruses to propagate and cause disease.

7 Feb 2023

Scientists discover how a high fat diet expels gut parasitic worm

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

Treating ovarian cancer with immunotherapy involving CAR T cells

Recent research revealed that CAR T-cell therapy, a particular type of cancer treatment in which the immune system’s T cells are directed to kill tumor cells, is successful in treating ovarian cancer in mice.

7 Feb 2023

Macrophages as new therapeutic target to address obesity-related diseases

Macrophages are immune system cells that control inflammation and tissue function in addition to being crucial in the early response to microbial infection. Since it aids in the repair of damaged tissue, inflammation is a natural physiological response.

6 Feb 2023

CAR T-cell therapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

Study sheds light on why lung tumors do not respond well to immunotherapy

Immunotherapy -; drug treatment that stimulates the immune system to attack tumors -; works well against some types of cancer, but it has shown mixed success against lung cancer.

6 Feb 2023

Non-immunosuppressive strategy mitigates immune-mediated intestinal diseases

The severity of immune-mediated intestinal diseases like graft-versus-host disease (GVHD) or inflammatory bowel disease is known to be associated with changes in the gut microbiome, but what causes such disruption in the microbial community is unknown.

3 Feb 2023

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Scientists at ISTA show that pathogens are adapting to social health care measures by ants.

3 Feb 2023

Cancer therapies improved by changing an antibody’s binding to a target

Before World Cancer Day (4th February), new research from the Centre for Cancer Immunology at the University of Southampton has demonstrated that altering how firmly an antibody attaches to a target can enhance cancer treatments.

2 Feb 2023

Scientists develop new design principles to improve cancer vaccines

A new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology at Northwestern University.

1 Feb 2023

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

1 Feb 2023

Study findings may pave way for personalized cancer treatment

In a step likely to advance personalized cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

31 Jan 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Scientists receive $10 million from HHMI for research on using viruses as therapeutic agents

Taking a bold step into a new era of biology, a team of scientists from the University of California San Diego, the J. Craig Venter Institute and Yale University has been awarded $10 million by the Howard Hughes Medical Institute to support research on using viruses as new therapeutic agents.

27 Jan 2023

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

27 Jan 2023

Persistent tumor mutation load may help predict outcome of novel immunotherapies

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

27 Jan 2023

Immune System News and Research

Importance of epigenetic regulation in the recovery of T cells

Novel compound curtails influenza virus replication

Combination of two types of immune cells helps predict response to cancer immunotherapy

Telomeres, mitochondria, and inflammation: Working in synergy to fight cancer

Protein that facilitates cancer-causing viruses dodge the immune system

Scientists discover how a high fat diet expels gut parasitic worm

Treating ovarian cancer with immunotherapy involving CAR T cells

Macrophages as new therapeutic target to address obesity-related diseases

CAR T-cell therapy effective in mice with ovarian cancer

Study sheds light on why lung tumors do not respond well to immunotherapy

Non-immunosuppressive strategy mitigates immune-mediated intestinal diseases

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Cancer therapies improved by changing an antibody’s binding to a target

Scientists develop new design principles to improve cancer vaccines

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Study findings may pave way for personalized cancer treatment

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

Scientists receive $10 million from HHMI for research on using viruses as therapeutic agents

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

Persistent tumor mutation load may help predict outcome of novel immunotherapies

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