Mutation News and Research

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New simpler, faster system for analyzing mutations in SARS-CoV-2

Although it is known that mutations in the SARS-CoV-2 genome occurred and spread, the effect of those mutations is not yet clear.

From Osaka University 14 Apr 2021

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations--mutations--that affect how genes act and function. Added together, millions of small genetic variations make it hard to predict how a particular mutation will impact any individual.

13 Apr 2021

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

According to a study, DNA defects in the energy “factories” of a cell increase the chance of survival in patients suffering from bowel cancer.

9 Apr 2021

PNA-based method is a key component of the gene editing toolkit

The Somatic Cell Gene Editing Consortium has given an update on the status of their initiative to design safer techniques to edit the genes of disease-relevant somatic cells.

8 Apr 2021

Eucalyptus can be genetically modified to prevent from invading native ecosystems

Eucalyptus, a pest-resistant evergreen valued for its hardy lumber and wellness-promoting oil, can be genetically modified not to reproduce sexually, a key step toward preventing the global tree plantation staple from invading native ecosystems.

8 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

The CRISPR-Chip technology was first introduced in 2019 by Dr. Kiana Aran, an Assistant Professor at Keck Graduate Institute (KGI).

6 Apr 2021

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Discovering a new genetic mutation in Schizophrenia

A new genetic mutation has been discovered in schizophrenia, and we spoke to Dr. Todd Lencz from the Feinstein Institutes for Medical Research to find out more.

From Northwell Health 1 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Study shows how WAVE2 protein maintains the immune system balance

Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.

26 Mar 2021

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Researchers have used an upgraded version of the gene-editing tool, CRISPR/Cas9, to knock out up to 12 genes in plants in just one go.

23 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Rare genetic variants contribute to increased risk for lung cancer

In the United States, lung cancer is the main cause of cancer death in both male and female populations.

19 Mar 2021

Genetic flaw shows promise for treating eye disease

A genetic flaw may hold the key to delay or prevent the onset of a serious eye disorder that can result in blindness and vision loss.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 17 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Mutation News and Research

New simpler, faster system for analyzing mutations in SARS-CoV-2

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

PNA-based method is a key component of the gene editing toolkit

Eucalyptus can be genetically modified to prevent from invading native ecosystems

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

High expression of cell death genes linked to increased risk of dying early from lung cancer

Discovering a new genetic mutation in Schizophrenia

New AI-based method can lead to faster, low-cost development of protein-based drugs

Study shows how WAVE2 protein maintains the immune system balance

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Low representation of minority groups in genomic databases may impact therapy selection

Rare genetic variants contribute to increased risk for lung cancer

Genetic flaw shows promise for treating eye disease

Study shows how human viruses are better adapted to infect certain tissues

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

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