CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

CRISPR technique can improve the quality of barley grain

A group of plant researchers has demonstrated the ability to rapidly enhance the quality of barley grain using a genetic tool called CRISPR or gene editing.

21 Sep 2020

Researchers compare developed carriers for delivery of genome editing tools

Scientists made a comparison of their developed carriers for delivery of genome editing (GE) tools with other available analogs.

18 Sep 2020

Research finds gene family critical to unlocking vertebrate evolution

New University of Colorado Boulder-led research finds that the traits that make vertebrates distinct from invertebrates were made possible by the emergence of a new set of genes 500 million years ago, documenting an important episode in evolution where new genes played a significant role in the evolution of novel traits in vertebrates.

17 Sep 2020

Researchers identify the targets of immune rejection

Human pluripotent stem cells (hPSCs) show promise in regenerative medicine for how they lead to the fraction of every other type of cells in the body.

17 Sep 2020

Study pinpoints specific genes that cause ovarian cancer

High-grade serious ovarian carcinoma is the fifth major cause of cancer-associated deaths in women in the United States.

14 Sep 2020

Study shows how genetic variants affect gene regulation and contribute to disease risk

The multi-institutional Genotype-Tissue Expression (GTEx) Consortium has published its final series of studies, as part of a final-phase initiative.

14 Sep 2020

CRISPR in a Box: New educational gene editing tool kit

Introducing CRISPR in a Box™ - it's not a new crunchy cereal or the latest snack - it's an educational tool kit consisting of state-of-the-science gene editing technology that could be coming to a school near you.

10 Sep 2020

Novel tool helps select the best gene-editing option

Scientists have improved one of the biggest scientific advancement of the past decade.

10 Sep 2020

Study reveals gene that provides resistance to tomatoes from bacterial speck disease

Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem in tomatoes over the last five years.

3 Sep 2020

Researchers develop new gene therapy for congenital blindness

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect.

3 Sep 2020

New method shows promise for treating diabetes and obesity

Obesity, the leading cause of type 2 diabetes and chronic illnesses, will collectively kill more people around the world in 2020 than COVID-19 coronavirus.

1 Sep 2020

New method accurately detects single gene mutation in a pool of 10,000 cells

Rare genetic mutations occurring in cells cannot be detected by existing sequencing techniques because these methods do not have the required sensitivity.

1 Sep 2020

Researchers perform massive and detailed cellular energy audit

TK Adenosine triphosphate, or ATP, is the cellular energy currency that is as valuable to the human body as the dollar is to the US economy. Too high or too low levels of ATP in some cell types have been linked to a variety of diseases.

31 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Novel gene editing approach removes latent herpes simplex virus 1

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

19 Aug 2020

Using genetic engineering to study evolutionary assimilation of foreign DNA in a new host

All life is subject to evolution in the form of mutations that change the DNA sequence of an organism's offspring, after which natural selection allows the 'fittest' mutants to survive and pass on their genes to future generations.

11 Aug 2020

Researchers use genome editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

11 Aug 2020

$1.2 million NIH grant awarded to create humanized mice susceptible to COVID-19

The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers.

11 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

Scientists explore the role of epigenetic regulator factors in embryonic development

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging".

5 Aug 2020