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Study Tracks How the Gut Microbiota Changes During First Three Months of Life

Details of how the gut microbiota changes during the first three months of life will be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

17 Apr 2023

New Peptide Blocks a Hyperactive Brain Enzyme Involved in Neurodegeneration

MIT neuroscientists have found a way to reverse neurodegeneration and other symptoms of Alzheimer's disease by interfering with an enzyme that is typically overactive in the brains of Alzheimer's patients.

17 Apr 2023

New Technique Identifies a Gene that Drives Clonal Expansion of Abnormal Cells

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

A New, Cost-Effective Therapy to Treat a Wide Range of Cancers

A potential immunotherapy method for treating metastatic melanoma is adoptive cell therapy (ACT). The method, which utilizes the use of immune cells extracted from the patient’s own tumors, could offer cancer patients new options for treatment by eschewing radiation therapies and harsh chemotherapy drugs.

11 Apr 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ways to treat AML, while preserving normal blood development.

10 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

10 Apr 2023

Novel Tridimensional Anticancer Agents Have the Ability to Overcome Drug Resistance in Cancer Cells

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

Novel Protein Involved in Tumor Suppression Identified

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

7 Apr 2023

Gut Microbiome and Enhanced Tumor Immune Response in Pancreatic Cancer Survivors

Even as pancreatic cancer treatments advance, only around 9% of patients live beyond five years. Scientists have failed to identify genetic distinctions that explain why some patients live for a long time and others do not, so they have moved their emphasis to the gut microbiome.

5 Apr 2023

Experts Unravel the Crystal Structure of CENP-E

Anticancer drugs are essential in cancer treatment, but their toxicity is not always restricted to cancer cells, resulting in serious side effects.

5 Apr 2023

Role of Engineered E. coli in Sending Therapeutic Nanobodies to the Gut

Numerous bacterium types have taken up residence in humans. Currently, research is concentrated on genetically modifying these bacteria to increase their inherent therapeutic qualities.

5 Apr 2023

Cellular Recycling Function in the Brain Slows Dramatically After Traumatic Brain Injury

Each year about 1.5 million people in the U.S. survive a traumatic brain injury due to a fall, car accident, or a sports injury, which can cause immediate and long-term disability.

5 Apr 2023

Experts Develop a New Mesoscopic Simulation Model of DNA Movement

The mesoscopic scale in physics and chemistry relates to the length scale on which the properties of a material or phenomenon can be researched without delving into the behaviour of individual atoms.

5 Apr 2023

New Shape-Shifting Antibiotics may Help Combat Drug-Resistant Superbugs

In the United States alone, drug-resistant bacteria and fungi infect almost 3 million people per year and kill about 35,000. Antibiotics are essential and effective, but in recent years overuse has led to some bacteria developing resistance to them.

5 Apr 2023

Study Offers New Insight into Genetic Factors Behind Premature Delivery and Gestational Duration

New knowledge of the genetic factors behind premature delivery and gestational duration has now emerged.

4 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

First Steps Driving Antibiotic Resistance Discovered

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

3 Apr 2023

Study brings into sharper focus the structural details of SARS-COV-2 virus

A new study led by Worcester Polytechnic Institute (WPI) brings into sharper focus the structural details of the COVID-19 virus, revealing an elliptical shape that "breathes," or changes shape, as it moves in the body.

31 Mar 2023