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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

MAGE Technology Helps Reveal the Potency of Antibiotics

By substituting each of the 20 amino acid alternatives found in nature for one of the 38 amino acid components that make up the rifampicin binding site on E. coli, the study authors were able to produce 760 distinct RNAP mutants. The development of this mutant pool was then examined under various circumstances, including rifampicin therapy.

31 Aug 2023

Gene Expression Analysis of Algae Sheds Light on Plant Terrestrialization

The Earth's surface is covered by plants. They make up the majority of biomass on land and exhibit a wide range of diversity, from mosses to trees.

31 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

Changes in RNA Induced by Different Chemical Modifications

RNA is essential for protein synthesis in the cell. According to a new study, RNA can be modified by numerous chemical modifications, the purpose of which is unknown to most people.

28 Aug 2023

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

New Cell Type Related to Organ Movement for Plant Selfing

Dr Yin-Zheng Wang of the Chinese Academy of Sciences' Institute of Botany is the lead of the study team that discovered movement in the Chirita pumila stigma and established a link between the motion and water sensitivity.

23 Aug 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

New Findings May Provide Useful Therapeutic Approach for Treating Breast Cancer Patients

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Stem Cells Used to Create Tooth Enamel in the Lab

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

16 Aug 2023

Targeting Long-read RNA Sequencing with Low-Cost Technology

Researchers at the Children’s Hospital of Philadelphia (CHOP) have created a flexible and affordable approach for targeted sequencing of full-length RNA molecules, which might hasten the development of novel diagnostics and therapies.

16 Aug 2023

Scaffolding Protein Helps in the Creation of Biomolecular Condensate

Biomolecular condensates are loosely organized assemblies that carry out a variety of vital tasks inside all live cells. However, the mechanism by which proteins and other biomolecules combine to create these assemblies within cells is not fully known.

16 Aug 2023

Researchers Identify Key Cells Involved in the Process of Cartilage Regeneration in Lizards

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

11 Aug 2023

A Surprisingly Quiet Discovery About Low-Noise Genes

While engaging in cell division research, Silke Hauf and members of her lab made a surprisingly quiet discovery.

11 Aug 2023

Researchers Find New Way to Defeat Gray Mold Without Toxic Chemicals

It's a mold that causes billions in crop losses every year, infecting berries, tomatoes and most other fruits and vegetables.

9 Aug 2023

RNA Modification in Driving Pancreatic Cancer Growth

RNA molecules can undergo chemical changes like m6A, which can have a significant influence on gene expression and affect several aspects of cancer development and progression

7 Aug 2023

New Way to Defeat the Gray Mold Without Showering Toxic Chemicals

It's a mold that causes billions in crop losses every year, infecting berries, tomatoes and most other fruits and vegetables. Now, researchers have found a way to defeat the mold without showering toxic chemicals on the crops.

4 Aug 2023

Study Offers Key Insights into the Structure of Neutral Mutations

An unexpected link between pure mathematics and genetics has been disclosed by an interdisciplinary group of mathematicians, physicists, engineers, and medical scientists. This helps disclose deep knowledge of the structure of neutral mutations and also the evolution of organisms.

2 Aug 2023

New Nanopore Technology Can Identify Single-Molecule Protein Variations

A group of researchers guided by the University of Oxford has made significant progress in detecting changes in protein structures. The method, which was published in Nature Nanotechnology, uses novel nanopore technology to detect structural variations at the single-molecule level, even deep within long protein chains.

2 Aug 2023

Single-Cell Sequencing Finds New Cell Types in the Visual Systems of Flies

Researchers from New York University have created a method that discovers and labels neurons throughout development, which has allowed them to identify novel cell types in the visual system of flies.

1 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023