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'Backpacks' Boost Immune Cells' Ability To Kill Cancer

Macrophages are immune cells that patrol the body looking for potential threats like viruses, bacteria, and cancer cells, and engulf and destroy them.

30 Apr 2020

A groundbreaking tool for efficient lipid analysis

Scientists are increasingly aiming to leverage the various functions of lipids in human bodies, for example, in blood coagulation or as blood fats, to better interpret and predict a host of diseases.

29 Apr 2020

Immune System Changes Occur Early In Development Of Multiple Myeloma

Before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergo dramatic shifts.

29 Apr 2020

Researchers study the evolution of multidrug-resistant bacteria

Although antibiotics are known to save lives, their use also supports the evolution and spread of antibiotic-resistant strains.

29 Apr 2020

Hyperosmotic stress induces phase separation of the proteasomes

Cellular proteostasis is regulated by a crucial proteolytic machine called proteasome via selective degradation of ubiquitylated proteins.

29 Apr 2020

Father's Toxoplasma infection may be transmitted to subsequent generations

Australian researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior.

28 Apr 2020

Research on rare molecule aims to improve treatments for cancer, HIV

Stanford University chemist Paul Wender and his colleagues are working to improve treatments for cancer, HIV and Alzheimer's - and they are betting that a drab, weedy marine invertebrate is the means to achieving that end.

28 Apr 2020

Def gene essential for maintaining liver homeostasis and regeneration capacity

Hepatocytes are responsible for diverse metabolic activities in a liver. Proper ribosome biogenesis is essential to sustain the function of hepatocytes.

28 Apr 2020

New Type Of Immune Cell Discovered In Breast Ducts

Melbourne breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process.

28 Apr 2020

New Staining Technique Visualizes Whole Organs And Bodies

A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology.

28 Apr 2020

Beta Cells From Stem Cells

The loss of insulin-secreting beta cells leads to type 1 diabetes. Islet cell transplantation has the potential to cure diabetes, but donors are rare.

28 Apr 2020

A Step Toward A Better Way To Make Gene Therapies To Attack Cancer, Genetic Disorders

A UCLA-led research team today reports that it has developed a new method for delivering DNA into stem cells and immune cells safely, rapidly and economically.

28 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

Study identifies role of interferon-stimulated genes in defense against hepatitis C viruses

The immune system responds immediately when a virus enters the cell, producing interferon—the signaling protein.

27 Apr 2020

Novel protein sensor controls the pathway of fat and sugar conversion in humans

Researchers in Pennsylvania and Texas have discovered a novel protein sensor that limits the amounts of fat and sugar that are converted into energy by human cells, during the starvation periods.

27 Apr 2020

Two nose cells may contribute to COVID-19 pandemic

Scientists have discovered two specific types of cells in the nose that are believed to be the initial infection points for COVID-19 coronavirus.

27 Apr 2020

NMR spectroscopy reveals mechanisms involved in DNA repair

The information contained in DNA is crucial for life. Hence, the integrity of the DNA has to be maintained extremely well.

27 Apr 2020

Scientists discover how tissues protect their DNA from mechanical stress

In everyday life, our tissues, for example skin and muscle, are stretched, pulled and compressed without causing damage to the cells or the DNA.

24 Apr 2020

Pancreatic tumors hijack basic cell mechanism for immune evasion

Pancreatic cancer cells use a normal waste removal process to hide tags on their surfaces that would otherwise let the immune system destroy them, a new study finds. Published online April 22 in Nature, the study results help to answer a longstanding question: why are pancreatic cancers so resistant to immunotherapies, which use the body's own immune defenses to fight cancer?

24 Apr 2020

Combination therapy encourages innate immune cells to eat GBM tumors

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020