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Study reveals the formation of tuft cells and their role in immunity

Chronic pancreatitis, or persistent inflammation of the pancreas, is a known risk factor that leads to the development of pancreatic cancer, which is the third-deadliest cancer in the United States.

20 Apr 2020

Chemical tools can regulate lipid concentration in living cells

Lipids have several crucial functions in the human body: They serve as messengers, which mediate the growth of cells and regulate the release of hormones.

20 Apr 2020

Study shows how human embryonic stem cells commit to early specialization

Scientists at the Francis Crick Institute have identified the point when stem cells in human embryos irreversibly commit to specialization.

20 Apr 2020

Advanced simulations show how to improve efficiency of gene therapy

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene.

20 Apr 2020

Stem Cells In Embryos Commit To Specialization Surprisingly Early

The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by researchers at the Francis Crick Institute.

20 Apr 2020

Autoimmunity Plays A Role In Parkinson's Disease

A new study co-led by scientists at the La Jolla Institute for Immunology (LJI) adds increasing evidence that Parkinson's disease is partly an autoimmune disease.

20 Apr 2020

Study Reveals Bile Metabolite Of Gut Microbes Boosts Immune Cells

A study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells.

20 Apr 2020

Histones Are Crucial For Adaptation To Cell Stress

The genetic material, DNA, of plants, animals, and humans is stored inside the cell, and DNA packing is guaranteed by proteins called histones.

20 Apr 2020

Designing Peptide Inhibitors For Possible COVID-19 Treatments

Scientists across the globe are rushing to find inhibitors of SARS-CoV-2, the new coronavirus behind the COVID-19 pandemic.

20 Apr 2020

Cancer Drug Resistance Study Raises Immune Red Flags

Sooner or later, most cancer patients develop resistance to chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

20 Apr 2020

Specialized proteins could help combat severe cytokine storms in COVID-19 patients

One of the defining features of COVID-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

17 Apr 2020

Sensitive technique makes it possible to study the delivery of RNA drugs

In recent years, RNA molecules, with the ability to affect or turn off pathogenic genes, have become promising drug candidates in several areas.

17 Apr 2020

Newly-discovered mitochondrial small protein is essential for energy production

A newly-discovered small protein in mitochondria is essential for energy production, report Duke-NUS researchers and their colleagues in the journal Nature Communications.

17 Apr 2020

Proving the existence of metabolons

For over four decades, researchers have proposed the presence of enzyme clusters, also called metabolons, which help facilitate several processes within cells.

17 Apr 2020

Mitochondrial protein contributes to degenerative diseases

Scientists and their collaborators from Duke-NUS Medical School (Duke NUS) have recently identified a novel small protein in mitochondria, which is essential for energy production.

17 Apr 2020

Experience Matters For Immune Cells

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer.

17 Apr 2020

Deadliest Malaria Strain Protects Itself From The Immune System

The parasite causing the most severe form of human malaria uses proteins to make red blood cells sticky, making it harder for the immune system to destroy it.

17 Apr 2020

Super-Charging Drug Development For COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures.

17 Apr 2020

Diagnostics, Meet CRISPR

The simplicity of urine sampling has been combined with the excellent sensing abilities of CRISPR to improve diagnostic testing for kidney transplant patients.

17 Apr 2020

Molecular network underlies the structures of critical cellular compartments

Networks are at the heart of everything from communications systems to pandemics. Now researchers have found that a unique type of network also underlies the structures of critical cellular compartments known as membraneless organelles.

16 Apr 2020