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UTSW researchers solve structure of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction.

16 Apr 2020

New optical imaging technology makes fluorescence microscopy more efficient

Scientists have been using fluorescence microscopy to study the inner workings of biological cells and organisms for decades.

16 Apr 2020

3D simulations will show how coronavirus spike protein binds to human cell receptors

Computational chemist Mahmoud Moradi will develop enhanced, 3D simulations of the molecular dynamics of coronavirus spike glycoproteins to gain better understanding of how the virus binds to human cells.

16 Apr 2020

Study shows how vulnerable cells armor themselves against infection

Cells in some of the body's most vulnerable entry routes to bacterial infection buffer themselves when the immune system detects danger by reorganizing the cholesterol on their surfaces, a new study led by UTSW scientists suggests.

16 Apr 2020

Single-cell cloning can lead to new therapies for COPD

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death around the world. Now, two internationally acclaimed stem cell experts have discovered a large number of abnormal stem cells found in the lungs of COPD patients.

16 Apr 2020

New study on transposable elements could help advance understanding of genetic evolution

There has been very little knowledge of ways in which transposable elements play a role in gene regulation. Transposable elements are small DNA pieces with the ability to replicate and scatter themselves in the genome.

16 Apr 2020

Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

Novel high-speed microscope successfully records neural activities

Our brain contains tens of billions of nerve cells (neurons) which constantly communicate with each other by sending chemical and electrical flashes, each lasting a short one millisecond (0.001 sec). In every millisecond, these billions of swift-flying flashes altogether traveling in a giant star-map in the brain that lights up a tortuous glittering pattern.

15 Apr 2020

Molecular causes of brain asymmetry revealed

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

15 Apr 2020

Scientists determine first 3D structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

15 Apr 2020

How human cells recognize undesirable guests

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

Clock protein moves in sync with temperature to coordinate rhythms in shoots, roots

Five years ago, researchers from the Centre for Research in Agricultural Genomics led by the CSIC Research Professor Paloma Mas made the breakthrough discovery that the circadian clocks in the growing tip of the plant shoot function in a similar way to the clocks in the mammalian brain, which in both cases are able to synchronize the daily rhythms of the cells in distal organs.

14 Apr 2020