Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

This study is led by Dr. Anjian Xu (Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University), Dr. Min Cong (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) and Dr. Junying Ding (Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University).

20 Feb 2023

Adding antioxidants to cell cultures for efficient production of antibodies

Researchers at the Department of Chemical Engineering, Indian Institute of Technology, India, have investigated the effects of oxidative stress on the production of monoclonal antibodies (mAbs), and how antioxidants can alleviate this stress to improve their performance.

16 Feb 2023

Innovative cancer therapy options with new cell death mechanism

Researchers from The University of Texas MD Anderson Cancer Center have described a previously unrecognized type of cell death called disulfidptosis in a study that was published in Nature Cell Biology.

7 Feb 2023

Effective anticancer strategy for selective killing of cancer cells

A study team headed by Dr Yuanliang Zhai from The University of Hong Kong’s (HKU) School of Biological Sciences and his associates from The Hong Kong University of Science and Technology (HKUST) and Institut Curie in France discovered a new mechanism of the human MCM2-7 complex in controlling replication initiation, which can be employed as a unique and effective anticancer method with the potential for selective death of cancer cells.

11 Jan 2023

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Aging and age-related diseases present a complex challenge to biomedical researchers.

20 Jul 2022

Zbtb38 removal results in early embryonic death

DNA methylation is a critical epigenetic alteration for mammalian development.

20 Apr 2022

Researchers introduce injectable stem cell assembly, likely to serve as the treatment for cartilage regeneration

Professor Qiuyu Zhang (Northwestern Polytechnical University), Professor Ki-Bum Lee (Rutgers University), and Professor Liang Kong (School of Stomatology, The Fourth Military Medical University) directed this research.

18 Apr 2022

Light-induced cellular apoptosis method can kill diseased cells without causing adverse reactions

Cancer has been the leading cause of death in Japan over the past 40 years. Despite the rise in patients due to the aging population, progresses in diagnosis and treatment are leading to higher survival rates.

1 Apr 2022

Study shows that mechanical stress help cancer cells metastasize

A recent study shows that compressing cancer cells through tight spaces makes them more violent and helps them avoid cell death.

9 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the uncontrolled growth of cancer cells.

25 Feb 2022

Study findings open new avenues for research into host-directed therapies for TB

A*STAR’s GIS and ID Labs have discovered KCNJ15, a gene linked to the human immune system’s ability to combat TB and maybe other infectious diseases.

18 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

Study reveals how the body controls inflammation during removal of damaged cells

A research team from Cologne and Osnabrück has investigated in detail how messenger substances signal inflammation during the removal of damaged cells in the body.

7 Feb 2022

Label-free device enables in-situ tracking of cell development and maturation

The biological intracellular microenvironment is diverse, consisting of several cell compartments and intracellular components.

20 Jan 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Simple, marine-dwelling creature shines light on cancer resistance

A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another intriguing characteristic: the ability to resist cancer.

24 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021