Breast Cancer News and Research

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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

Tokyo Metropolitan University Decodes DNA Repair Mechanisms

Tokyo Metropolitan University researchers have uncovered crucial aspects of the DNA repair mechanism within human bodies.

16 Nov 2023

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

14 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

Lactate Oxidase Nanocapsules Help the Immune System to Fight and Kill Solid Tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

13 Oct 2023

Attaining Precision Nutrition Through Omega-3 Fatty Acids

Researchers at the School of Medicine discovered new information on how the genes of African-Americans and Hispanic-Americans affect their capacity to utilize Omega-3 and Omega-6 fatty acids for optimal health.

12 Oct 2023

Scientists Explain How Enhancer Reprogramming Promotes Tumor Cell Growth

Cancer cells can boost tumor development by hijacking enhancer DNA, which is typically utilized when tissues and organs form, according to researchers at the University of Toronto (U of T).

29 Sep 2023

Bioengineered Enzyme-Based Scissors can Selectively Remove Mucins Off Cancer Cells

Cancer cells can evade the body's immune defenses by exploiting a normally helpful and ubiquitous group of molecules known as mucins.

24 Aug 2023

New Findings May Provide Useful Therapeutic Approach for Treating Breast Cancer Patients

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

New Method Reconstructs 3D Tissue From 2D Slices

Imagine a few roughly cut slices of bread on a plate. With just those slices, could you picture, in fine detail, the loaf they came from?

18 Aug 2023

Targeting Long-read RNA Sequencing with Low-Cost Technology

Researchers at the Children’s Hospital of Philadelphia (CHOP) have created a flexible and affordable approach for targeted sequencing of full-length RNA molecules, which might hasten the development of novel diagnostics and therapies.

16 Aug 2023

New Mechanism Regulating Tumor Growth in the Skeleton Identified

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.

11 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Method Facilitates Early Detection and Localization of Tumors

To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.

26 Jul 2023

Research may Offer a New Way to Break Through Cancer's Hypoxia-Induced Defenses

For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. Cancer cells, on the other hand, can thrive in these hypoxic conditions, which render tumors less susceptible to anti-cancer treatments, including radiation.

11 Jul 2023

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

7 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023